HCSGD entry for ALPPL2


1. General information

Official gene symbolALPPL2
Entrez ID251
Gene full namealkaline phosphatase, placental-like 2
Other gene symbolsALPG ALPPL GCAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004035Alkaline phosphatase activityNASmolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0016311DephosphorylationNASbiological_process
GO:0031225Anchored component of membraneIEAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67975013870.74792373390.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0182313570
GSE13712_SHEARDown-0.1528941288
GSE13712_STATICDown-0.0620627224
GSE19018Up0.0813465884
GSE19899_A1Up0.0528306043
GSE19899_A2Up0.2599586942
PubMed_21979375_A1Down-0.0332950917
PubMed_21979375_A2Down-0.1482297285
GSE35957Up0.1408097005
GSE36640Down-0.0121332877
GSE54402Down-0.0011289602
GSE9593Up0.1745721538
GSE43922Up0.0644764970
GSE24585Up0.2235399432
GSE37065Down-0.1759212732
GSE28863_A1Down-0.2494953290
GSE28863_A2Up0.0515265269
GSE28863_A3Up0.0173973855
GSE28863_A4Up0.0504237131
GSE48662Down-0.0007667947

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

LevamisoleDB00848 APRD01067
AmifostineDB01143 APRD00021

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT021509Reporter assay;MicroarrayFunctional MTI21351259
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.