HCSGD entry for ALPPL2


1. General information

Official gene symbolALPPL2
Entrez ID251
Gene full namealkaline phosphatase, placental-like 2
Other gene symbolsALPG ALPPL GCAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004035Alkaline phosphatase activityNASmolecular_function
GO:0005886Plasma membraneIEAcellular_component
GO:0016311DephosphorylationNASbiological_process
GO:0031225Anchored component of membraneIEAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67975013870.74792373390.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0182313570
GSE13712_SHEARDown-0.1528941288
GSE13712_STATICDown-0.0620627224
GSE19018Up0.0813465884
GSE19899_A1Up0.0528306043
GSE19899_A2Up0.2599586942
PubMed_21979375_A1Down-0.0332950917
PubMed_21979375_A2Down-0.1482297285
GSE35957Up0.1408097005
GSE36640Down-0.0121332877
GSE54402Down-0.0011289602
GSE9593Up0.1745721538
GSE43922Up0.0644764970
GSE24585Up0.2235399432
GSE37065Down-0.1759212732
GSE28863_A1Down-0.2494953290
GSE28863_A2Up0.0515265269
GSE28863_A3Up0.0173973855
GSE28863_A4Up0.0504237131
GSE48662Down-0.0007667947

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

LevamisoleDB00848 APRD01067
AmifostineDB01143 APRD00021

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT021509Reporter assay;MicroarrayFunctional MTI21351259
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.