HCSGD entry for FKBP8
1. General information
| Official gene symbol | FKBP8 |
|---|---|
| Entrez ID | 23770 |
| Gene full name | FK506 binding protein 8, 38kDa |
| Other gene symbols | FKBP38 FKBPr38 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000413 | Protein peptidyl-prolyl isomerization | IBA | biological_process |
| GO:0001708 | Cell fate specification | IEA | biological_process |
| GO:0003755 | Peptidyl-prolyl cis-trans isomerase activity | IBA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005528 | FK506 binding | IBA | molecular_function |
| GO:0005740 | Mitochondrial envelope | IBA IEA | cellular_component |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007224 | Smoothened signaling pathway | IEA | biological_process |
| GO:0010468 | Regulation of gene expression | IEA | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0018208 | Peptidyl-proline modification | IBA | biological_process |
| GO:0021904 | Dorsal/ventral neural tube patterning | IEA | biological_process |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | IBA IEA | cellular_component |
| GO:0030513 | Positive regulation of BMP signaling pathway | IEA | biological_process |
| GO:0031966 | Mitochondrial membrane | IEA | cellular_component |
| GO:0035264 | Multicellular organism growth | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | TAS | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0043010 | Camera-type eye development | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2644944417 | 0.2845850538 | 0.9593225313 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0438231681 |
| GSE13712_SHEAR | Down | -0.2579563380 |
| GSE13712_STATIC | Down | -0.2111251581 |
| GSE19018 | Up | 0.4511351593 |
| GSE19899_A1 | Down | -0.1897634749 |
| GSE19899_A2 | Up | 0.2427652524 |
| PubMed_21979375_A1 | Up | 0.0316029912 |
| PubMed_21979375_A2 | Up | 0.9336837813 |
| GSE35957 | Up | 0.0995593228 |
| GSE36640 | Up | 0.0416288817 |
| GSE54402 | Down | -0.0110716557 |
| GSE9593 | Up | 0.3452154613 |
| GSE43922 | Down | -0.1449246841 |
| GSE24585 | Down | -0.1436694984 |
| GSE37065 | Down | -0.2087565938 |
| GSE28863_A1 | Down | -0.1018254240 |
| GSE28863_A2 | Down | -0.1558968127 |
| GSE28863_A3 | Down | -0.4329785038 |
| GSE28863_A4 | Down | -0.0328342569 |
| GSE48662 | Up | 0.7943772234 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017629 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-1301-3p | MIMAT0005797 | MIRT036002 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-421 | MIMAT0003339 | MIRT039410 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049630 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052520 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
