HCSGD entry for FKBP8


1. General information

Official gene symbolFKBP8
Entrez ID23770
Gene full nameFK506 binding protein 8, 38kDa
Other gene symbolsFKBP38 FKBPr38
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000413Protein peptidyl-prolyl isomerizationIBAbiological_process
GO:0001708Cell fate specificationIEAbiological_process
GO:0003755Peptidyl-prolyl cis-trans isomerase activityIBA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005528FK506 bindingIBAmolecular_function
GO:0005740Mitochondrial envelopeIBA IEAcellular_component
GO:0006457Protein foldingIEAbiological_process
GO:0006915Apoptotic processIEAbiological_process
GO:0007224Smoothened signaling pathwayIEAbiological_process
GO:0010468Regulation of gene expressionIEAbiological_process
GO:0016032Viral processIEAbiological_process
GO:0018208Peptidyl-proline modificationIBAbiological_process
GO:0021904Dorsal/ventral neural tube patterningIEAbiological_process
GO:0030176Integral component of endoplasmic reticulum membraneIBA IEAcellular_component
GO:0030513Positive regulation of BMP signaling pathwayIEAbiological_process
GO:0031966Mitochondrial membraneIEAcellular_component
GO:0035264Multicellular organism growthIEAbiological_process
GO:0035556Intracellular signal transductionTASbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0043010Camera-type eye developmentIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26449444170.28458505380.95932253131.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0438231681
GSE13712_SHEARDown-0.2579563380
GSE13712_STATICDown-0.2111251581
GSE19018Up0.4511351593
GSE19899_A1Down-0.1897634749
GSE19899_A2Up0.2427652524
PubMed_21979375_A1Up0.0316029912
PubMed_21979375_A2Up0.9336837813
GSE35957Up0.0995593228
GSE36640Up0.0416288817
GSE54402Down-0.0110716557
GSE9593Up0.3452154613
GSE43922Down-0.1449246841
GSE24585Down-0.1436694984
GSE37065Down-0.2087565938
GSE28863_A1Down-0.1018254240
GSE28863_A2Down-0.1558968127
GSE28863_A3Down-0.4329785038
GSE28863_A4Down-0.0328342569
GSE48662Up0.7943772234

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017629MicroarrayFunctional MTI (Weak)18185580
hsa-miR-1301-3pMIMAT0005797MIRT036002CLASHFunctional MTI (Weak)23622248
hsa-miR-421MIMAT0003339MIRT039410CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049630CLASHFunctional MTI (Weak)23622248
hsa-let-7a-5pMIMAT0000062MIRT052520CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.