HCSGD entry for DAPK2

1. General information

Official gene symbolDAPK2
Entrez ID23604
Gene full namedeath-associated protein kinase 2
Other gene symbolsDRP-1 DRP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004672Protein kinase activityIEAmolecular_function
GO:0004674Protein serine/threonine kinase activityTASmolecular_function
GO:0005516Calmodulin bindingIDAmolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0006468Protein phosphorylationIDAbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0010506Regulation of autophagyTASbiological_process
GO:0031410Cytoplasmic vesicleIEAcellular_component
GO:0034423Autophagic vacuole lumenIEAcellular_component
GO:0035556Intracellular signal transductionIDAbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0042981Regulation of apoptotic processTASbiological_process
GO:0043276AnoikisIMPbiological_process
GO:0046777Protein autophosphorylationTASbiological_process
GO:1900119Positive regulation of execution phase of apoptosisIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72578886440.29490698300.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0253053507
GSE13712_SHEARUp0.0688827287
GSE13712_STATICDown-0.2166439491
GSE19018Down-0.5977228064
GSE19899_A1Down-0.1440345167
GSE19899_A2Up0.0893443275
PubMed_21979375_A1Down-0.2947680210
PubMed_21979375_A2Up0.1338916452
GSE35957Down-0.3418215634
GSE36640Up0.3700776352
GSE54402Up0.0902870125
GSE9593Down-0.0367324084
GSE43922Up0.1324642812
GSE24585Down-0.0373495494
GSE37065Down-0.1450388128
GSE28863_A1Up0.1701958758
GSE28863_A2Down-0.1467142232
GSE28863_A3Up0.2854483603
GSE28863_A4Down-0.0693230110
GSE48662Up0.0321925710

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016960MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.