HCSGD entry for DAPK2
1. General information
| Official gene symbol | DAPK2 |
|---|---|
| Entrez ID | 23604 |
| Gene full name | death-associated protein kinase 2 |
| Other gene symbols | DRP-1 DRP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | TAS | molecular_function |
| GO:0005516 | Calmodulin binding | IDA | molecular_function |
| GO:0005524 | ATP binding | IDA IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0010506 | Regulation of autophagy | TAS | biological_process |
| GO:0031410 | Cytoplasmic vesicle | IEA | cellular_component |
| GO:0034423 | Autophagic vacuole lumen | IEA | cellular_component |
| GO:0035556 | Intracellular signal transduction | IDA | biological_process |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042981 | Regulation of apoptotic process | TAS | biological_process |
| GO:0043276 | Anoikis | IMP | biological_process |
| GO:0046777 | Protein autophosphorylation | TAS | biological_process |
| GO:1900119 | Positive regulation of execution phase of apoptosis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7257888644 | 0.2949069830 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0253053507 |
| GSE13712_SHEAR | Up | 0.0688827287 |
| GSE13712_STATIC | Down | -0.2166439491 |
| GSE19018 | Down | -0.5977228064 |
| GSE19899_A1 | Down | -0.1440345167 |
| GSE19899_A2 | Up | 0.0893443275 |
| PubMed_21979375_A1 | Down | -0.2947680210 |
| PubMed_21979375_A2 | Up | 0.1338916452 |
| GSE35957 | Down | -0.3418215634 |
| GSE36640 | Up | 0.3700776352 |
| GSE54402 | Up | 0.0902870125 |
| GSE9593 | Down | -0.0367324084 |
| GSE43922 | Up | 0.1324642812 |
| GSE24585 | Down | -0.0373495494 |
| GSE37065 | Down | -0.1450388128 |
| GSE28863_A1 | Up | 0.1701958758 |
| GSE28863_A2 | Down | -0.1467142232 |
| GSE28863_A3 | Up | 0.2854483603 |
| GSE28863_A4 | Down | -0.0693230110 |
| GSE48662 | Up | 0.0321925710 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016960 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
