HCSGD entry for CDC42EP4


1. General information

Official gene symbolCDC42EP4
Entrez ID23580
Gene full nameCDC42 effector protein (Rho GTPase binding) 4
Other gene symbolsBORG4 CEP4 KAIA1777
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005737CytoplasmIEAcellular_component
GO:0007266Rho protein signal transductionIEAbiological_process
GO:0008360Regulation of cell shapeIDAbiological_process
GO:0012505Endomembrane systemIEAcellular_component
GO:0015629Actin cytoskeletonIDAcellular_component
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0016020MembraneIEAcellular_component
GO:0017049GTP-Rho bindingNASmolecular_function
GO:0031274Positive regulation of pseudopodium assemblyIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.35408565780.04824663200.99999024730.4113701328

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2432266457
GSE13712_SHEARUp0.7383765000
GSE13712_STATICUp0.3115543462
GSE19018Up0.2304530115
GSE19899_A1Down-0.5585498860
GSE19899_A2Down-1.1530353755
PubMed_21979375_A1Down-0.6314625235
PubMed_21979375_A2Down-0.5989252159
GSE35957Down-0.6756499466
GSE36640Down-0.6544763590
GSE54402Down-0.4759789535
GSE9593Down-0.3901411308
GSE43922Down-0.4282699933
GSE24585Up0.3669325562
GSE37065Up0.0748940899
GSE28863_A1Up0.7330484346
GSE28863_A2Down-0.1523081672
GSE28863_A3Down-0.1302321381
GSE28863_A4Up0.1297331337
GSE48662Up0.0788799583

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016422MicroarrayFunctional MTI (Weak)20304954
hsa-miR-335-5pMIMAT0000765MIRT017707MicroarrayFunctional MTI (Weak)18185580
hsa-miR-7-5pMIMAT0000252MIRT025742MicroarrayFunctional MTI (Weak)19073608
hsa-miR-1229-3pMIMAT0005584MIRT036315CLASHFunctional MTI (Weak)23622248
hsa-miR-941MIMAT0004984MIRT036563CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.