HCSGD entry for CDC42EP4
1. General information
| Official gene symbol | CDC42EP4 |
|---|---|
| Entrez ID | 23580 |
| Gene full name | CDC42 effector protein (Rho GTPase binding) 4 |
| Other gene symbols | BORG4 CEP4 KAIA1777 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0007266 | Rho protein signal transduction | IEA | biological_process |
| GO:0008360 | Regulation of cell shape | IDA | biological_process |
| GO:0012505 | Endomembrane system | IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0017049 | GTP-Rho binding | NAS | molecular_function |
| GO:0031274 | Positive regulation of pseudopodium assembly | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3540856578 | 0.0482466320 | 0.9999902473 | 0.4113701328 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2432266457 |
| GSE13712_SHEAR | Up | 0.7383765000 |
| GSE13712_STATIC | Up | 0.3115543462 |
| GSE19018 | Up | 0.2304530115 |
| GSE19899_A1 | Down | -0.5585498860 |
| GSE19899_A2 | Down | -1.1530353755 |
| PubMed_21979375_A1 | Down | -0.6314625235 |
| PubMed_21979375_A2 | Down | -0.5989252159 |
| GSE35957 | Down | -0.6756499466 |
| GSE36640 | Down | -0.6544763590 |
| GSE54402 | Down | -0.4759789535 |
| GSE9593 | Down | -0.3901411308 |
| GSE43922 | Down | -0.4282699933 |
| GSE24585 | Up | 0.3669325562 |
| GSE37065 | Up | 0.0748940899 |
| GSE28863_A1 | Up | 0.7330484346 |
| GSE28863_A2 | Down | -0.1523081672 |
| GSE28863_A3 | Down | -0.1302321381 |
| GSE28863_A4 | Up | 0.1297331337 |
| GSE48662 | Up | 0.0788799583 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016422 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017707 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025742 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036315 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-941 | MIMAT0004984 | MIRT036563 | CLASH | Functional MTI (Weak) | 23622248 |
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