HCSGD entry for FOSB

1. General information

Official gene symbolFOSB
Entrez ID2354
Gene full nameFBJ murine osteosarcoma viral oncogene homolog B
Other gene symbolsAP-1 G0S3 GOS3 GOSB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0003677DNA bindingIEA TASmolecular_function
GO:0003690Double-stranded DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterIEAbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0007565Female pregnancyIEAbiological_process
GO:0007610BehaviorTASbiological_process
GO:0008134Transcription factor bindingTASmolecular_function
GO:0009612Response to mechanical stimulusIEAbiological_process
GO:0032570Response to progesteroneIEAbiological_process
GO:0032870Cellular response to hormone stimulusIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0043278Response to morphineIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0051412Response to corticosteroneIEAbiological_process
GO:0051591Response to cAMPIEAbiological_process
GO:0071277Cellular response to calcium ionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00569870830.08492257510.19851176470.5529906258

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-3.3735518679
GSE13712_SHEARDown-0.7364892360
GSE13712_STATICUp0.1744819055
GSE19018Down-1.4916818619
GSE19899_A1Up0.1370867944
GSE19899_A2Up0.4223404692
PubMed_21979375_A1Up2.6490286361
PubMed_21979375_A2Up0.3366690713
GSE35957Up0.1986127072
GSE36640Up0.0987105286
GSE54402Up1.3247605147
GSE9593Down-0.1408989236
GSE43922Up0.2736846877
GSE24585Up0.0691731308
GSE37065Up0.4180713857
GSE28863_A1Up1.4544676766
GSE28863_A2Down-1.1095645160
GSE28863_A3Down-0.3257979126
GSE28863_A4Up0.5177672299
GSE48662Up0.3641664137

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-224-5pMIMAT0000281MIRT003234Luciferase reporter assayNon-Functional MTI20065103
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.