HCSGD entry for FOSB

1. General information

Official gene symbolFOSB
Entrez ID2354
Gene full nameFBJ murine osteosarcoma viral oncogene homolog B
Other gene symbolsAP-1 G0S3 GOS3 GOSB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0003677DNA bindingIEA TASmolecular_function
GO:0003690Double-stranded DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006366Transcription from RNA polymerase II promoterIEAbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0007565Female pregnancyIEAbiological_process
GO:0007610BehaviorTASbiological_process
GO:0008134Transcription factor bindingTASmolecular_function
GO:0009612Response to mechanical stimulusIEAbiological_process
GO:0032570Response to progesteroneIEAbiological_process
GO:0032870Cellular response to hormone stimulusIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0043278Response to morphineIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0051412Response to corticosteroneIEAbiological_process
GO:0051591Response to cAMPIEAbiological_process
GO:0071277Cellular response to calcium ionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00569870830.08492257510.19851176470.5529906258

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-3.3735518679
GSE13712_SHEARDown-0.7364892360
GSE13712_STATICUp0.1744819055
GSE19018Down-1.4916818619
GSE19899_A1Up0.1370867944
GSE19899_A2Up0.4223404692
PubMed_21979375_A1Up2.6490286361
PubMed_21979375_A2Up0.3366690713
GSE35957Up0.1986127072
GSE36640Up0.0987105286
GSE54402Up1.3247605147
GSE9593Down-0.1408989236
GSE43922Up0.2736846877
GSE24585Up0.0691731308
GSE37065Up0.4180713857
GSE28863_A1Up1.4544676766
GSE28863_A2Down-1.1095645160
GSE28863_A3Down-0.3257979126
GSE28863_A4Up0.5177672299
GSE48662Up0.3641664137

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-224-5pMIMAT0000281MIRT003234Luciferase reporter assayNon-Functional MTI20065103
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.