HCSGD entry for WWC1
1. General information
| Official gene symbol | WWC1 |
|---|---|
| Entrez ID | 23286 |
| Gene full name | WW and C2 domain containing 1 |
| Other gene symbols | HBEBP3 HBEBP36 KIBRA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003713 | Transcription coactivator activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0016477 | Cell migration | IDA | biological_process |
| GO:0030674 | Protein binding, bridging | IEA | molecular_function |
| GO:0032587 | Ruffle membrane | IDA | cellular_component |
| GO:0035329 | Hippo signaling | TAS | biological_process |
| GO:0035330 | Regulation of hippo signaling | IMP | biological_process |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0043410 | Positive regulation of MAPK cascade | IDA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8702067095 | 0.1260296645 | 0.9999902473 | 0.6831191928 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0289323589 |
| GSE13712_SHEAR | Down | -0.0317240420 |
| GSE13712_STATIC | Down | -0.1383390168 |
| GSE19018 | Up | 0.0860122547 |
| GSE19899_A1 | Down | -0.0718520402 |
| GSE19899_A2 | Up | 0.2235906036 |
| PubMed_21979375_A1 | Up | 0.5007174691 |
| PubMed_21979375_A2 | Up | 0.0182951587 |
| GSE35957 | Down | -0.1703403854 |
| GSE36640 | Down | -0.9567852568 |
| GSE54402 | Down | -0.2049690305 |
| GSE9593 | Down | -0.1268369848 |
| GSE43922 | Up | 0.0918334904 |
| GSE24585 | Down | -1.0288650813 |
| GSE37065 | Down | -0.2350021042 |
| GSE28863_A1 | Down | -0.0160846864 |
| GSE28863_A2 | Up | 0.0526339839 |
| GSE28863_A3 | Up | 0.2758819719 |
| GSE28863_A4 | Up | 0.0349148498 |
| GSE48662 | Down | -0.3909976916 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019952 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020928 | Reporter assay;Other | Functional MTI | 20584899 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
