HCSGD entry for WWC1


1. General information

Official gene symbolWWC1
Entrez ID23286
Gene full nameWW and C2 domain containing 1
Other gene symbolsHBEBP3 HBEBP36 KIBRA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0016477Cell migrationIDAbiological_process
GO:0030674Protein binding, bridgingIEAmolecular_function
GO:0032587Ruffle membraneIDAcellular_component
GO:0035329Hippo signalingTASbiological_process
GO:0035330Regulation of hippo signalingIMPbiological_process
GO:0043234Protein complexIEAcellular_component
GO:0043410Positive regulation of MAPK cascadeIDAbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.87020670950.12602966450.99999024730.6831191928

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0289323589
GSE13712_SHEARDown-0.0317240420
GSE13712_STATICDown-0.1383390168
GSE19018Up0.0860122547
GSE19899_A1Down-0.0718520402
GSE19899_A2Up0.2235906036
PubMed_21979375_A1Up0.5007174691
PubMed_21979375_A2Up0.0182951587
GSE35957Down-0.1703403854
GSE36640Down-0.9567852568
GSE54402Down-0.2049690305
GSE9593Down-0.1268369848
GSE43922Up0.0918334904
GSE24585Down-1.0288650813
GSE37065Down-0.2350021042
GSE28863_A1Down-0.0160846864
GSE28863_A2Up0.0526339839
GSE28863_A3Up0.2758819719
GSE28863_A4Up0.0349148498
GSE48662Down-0.3909976916

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT019952MicroarrayFunctional MTI (Weak)20215506
hsa-miR-155-5pMIMAT0000646MIRT020928Reporter assay;OtherFunctional MTI20584899
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.