HCSGD entry for FBXL7

1. General information

Official gene symbolFBXL7
Entrez ID23194
Gene full nameF-box and leucine-rich repeat protein 7
Other gene symbolsFBL6 FBL7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleIEA ISSbiological_process
GO:0000151Ubiquitin ligase complexNAScellular_component
GO:0004842Ubiquitin-protein ligase activityNASmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005813CentrosomeIEA ISScellular_component
GO:0006511Ubiquitin-dependent protein catabolic processNASbiological_process
GO:0007067MitosisIEA ISSbiological_process
GO:0008283Cell proliferationIEA ISSbiological_process
GO:0016567Protein ubiquitinationISSbiological_process
GO:0019005SCF ubiquitin ligase complexIEA ISScellular_component
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic processIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82922437980.02169106040.99999024730.2840449751

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6646051750
GSE13712_SHEARDown-0.1982554749
GSE13712_STATICDown-0.2655718853
GSE19018Up0.3884887871
GSE19899_A1Down-0.0427753042
GSE19899_A2Down-1.1267431620
PubMed_21979375_A1Down-1.3058516692
PubMed_21979375_A2Down-0.6568022390
GSE35957Down-0.9058980412
GSE36640Down-0.3951203272
GSE54402Down-0.3176421378
GSE9593Up0.5213188770
GSE43922Down-0.1089930191
GSE24585Up0.0577195143
GSE37065Down-0.0333964142
GSE28863_A1Up0.6241068412
GSE28863_A2Up0.0666130046
GSE28863_A3Down-0.3201543157
GSE28863_A4Down-0.2382743139
GSE48662Up0.5230465040

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.