HCSGD entry for FBXL7


1. General information

Official gene symbolFBXL7
Entrez ID23194
Gene full nameF-box and leucine-rich repeat protein 7
Other gene symbolsFBL6 FBL7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleIEA ISSbiological_process
GO:0000151Ubiquitin ligase complexNAScellular_component
GO:0004842Ubiquitin-protein ligase activityNASmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005813CentrosomeIEA ISScellular_component
GO:0006511Ubiquitin-dependent protein catabolic processNASbiological_process
GO:0007067MitosisIEA ISSbiological_process
GO:0008283Cell proliferationIEA ISSbiological_process
GO:0016567Protein ubiquitinationISSbiological_process
GO:0019005SCF ubiquitin ligase complexIEA ISScellular_component
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic processIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82922437980.02169106040.99999024730.2840449751

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.6646051750
GSE13712_SHEARDown-0.1982554749
GSE13712_STATICDown-0.2655718853
GSE19018Up0.3884887871
GSE19899_A1Down-0.0427753042
GSE19899_A2Down-1.1267431620
PubMed_21979375_A1Down-1.3058516692
PubMed_21979375_A2Down-0.6568022390
GSE35957Down-0.9058980412
GSE36640Down-0.3951203272
GSE54402Down-0.3176421378
GSE9593Up0.5213188770
GSE43922Down-0.1089930191
GSE24585Up0.0577195143
GSE37065Down-0.0333964142
GSE28863_A1Up0.6241068412
GSE28863_A2Up0.0666130046
GSE28863_A3Down-0.3201543157
GSE28863_A4Down-0.2382743139
GSE48662Up0.5230465040

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.