HCSGD entry for RCOR1

1. General information

Official gene symbolRCOR1
Entrez ID23186
Gene full nameREST corepressor 1
Other gene symbolsCOREST RCOR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptionIDAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEA NAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0016032Viral processIEAbiological_process
GO:0017053Transcriptional repressor complexIDAcellular_component
GO:0030218Erythrocyte differentiationIEAbiological_process
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0045654Positive regulation of megakaryocyte differentiationIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0070933Histone H4 deacetylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11297327610.75393490750.69228216951.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5958239236
GSE13712_SHEARUp0.2138437508
GSE13712_STATICUp0.0397197159
GSE19018Up0.0630344807
GSE19899_A1Up0.4280143782
GSE19899_A2Up0.2700320124
PubMed_21979375_A1Up0.3227431323
PubMed_21979375_A2Up0.1454628355
GSE35957Down-0.3108420907
GSE36640Up0.0951156340
GSE54402Up0.0081297084
GSE9593Down-0.0502206551
GSE43922Up0.0703604044
GSE24585Up0.7103970313
GSE37065Down-0.0452068439
GSE28863_A1Up0.5123036039
GSE28863_A2Up0.3988575614
GSE28863_A3Down-0.3600287319
GSE28863_A4Up0.0757930754
GSE48662Down-0.3580732458

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT001506pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-9-3pMIMAT0000442MIRT003911Luciferase reporter assay//Western blotFunctional MTI19118166
hsa-miR-22-3pMIMAT0000077MIRT007220Luciferase reporter assayFunctional MTI23349832
hsa-miR-25-3pMIMAT0000081MIRT050248CLASHFunctional MTI (Weak)23622248
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    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-9-3pMIMAT0000442NAhsa-miR-9*{Western blot}{overexpression by miRNA precursor transfection}19118166
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.