HCSGD entry for RCOR1

1. General information

Official gene symbolRCOR1
Entrez ID23186
Gene full nameREST corepressor 1
Other gene symbolsCOREST RCOR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptionIDAmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEA NAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0016032Viral processIEAbiological_process
GO:0017053Transcriptional repressor complexIDAcellular_component
GO:0030218Erythrocyte differentiationIEAbiological_process
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0045654Positive regulation of megakaryocyte differentiationIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0070933Histone H4 deacetylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11297327610.75393490750.69228216951.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.5958239236
GSE13712_SHEARUp0.2138437508
GSE13712_STATICUp0.0397197159
GSE19018Up0.0630344807
GSE19899_A1Up0.4280143782
GSE19899_A2Up0.2700320124
PubMed_21979375_A1Up0.3227431323
PubMed_21979375_A2Up0.1454628355
GSE35957Down-0.3108420907
GSE36640Up0.0951156340
GSE54402Up0.0081297084
GSE9593Down-0.0502206551
GSE43922Up0.0703604044
GSE24585Up0.7103970313
GSE37065Down-0.0452068439
GSE28863_A1Up0.5123036039
GSE28863_A2Up0.3988575614
GSE28863_A3Down-0.3600287319
GSE28863_A4Up0.0757930754
GSE48662Down-0.3580732458

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT001506pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-9-3pMIMAT0000442MIRT003911Luciferase reporter assay//Western blotFunctional MTI19118166
hsa-miR-22-3pMIMAT0000077MIRT007220Luciferase reporter assayFunctional MTI23349832
hsa-miR-25-3pMIMAT0000081MIRT050248CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-9-3pMIMAT0000442NAhsa-miR-9*{Western blot}{overexpression by miRNA precursor transfection}19118166
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.