HCSGD entry for EPB41L3

1. General information

Official gene symbolEPB41L3
Entrez ID23136
Gene full nameerythrocyte membrane protein band 4.1-like 3
Other gene symbols4.1B DAL-1 DAL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002175Protein localization to paranode region of axonIEA ISSbiological_process
GO:0003779Actin bindingIEAmolecular_function
GO:0005198Structural molecule activityIEAmolecular_function
GO:0005200Structural constituent of cytoskeletonTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneNAScellular_component
GO:0005911Cell-cell junctionIDAcellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0007016Cytoskeletal anchoring at plasma membraneTASbiological_process
GO:0008150Biological_processNDbiological_process
GO:0008360Regulation of cell shapeIEA ISSbiological_process
GO:0019898Extrinsic component of membraneIEAcellular_component
GO:0030673AxolemmaIEA ISScellular_component
GO:0030865Cortical cytoskeleton organizationTASbiological_process
GO:0030866Cortical actin cytoskeleton organizationIEAbiological_process
GO:0030913Paranodal junction assemblyIEA ISSbiological_process
GO:0033270Paranode region of axonIEA ISScellular_component
GO:0043217Myelin maintenanceIEA ISSbiological_process
GO:0044224Juxtaparanode region of axonIEA ISScellular_component
GO:0048812Neuron projection morphogenesisIEA ISSbiological_process
GO:0071205Protein localization to juxtaparanode region of axonIEA ISSbiological_process
GO:0072659Protein localization to plasma membraneIEA ISSbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15167599640.10977876980.77732988710.6343549945

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1955595262
GSE13712_SHEARUp0.3974920660
GSE13712_STATICUp0.5442158842
GSE19018Down-0.1059018676
GSE19899_A1Down-0.2569753411
GSE19899_A2Up0.6162699573
PubMed_21979375_A1Up0.3148893442
PubMed_21979375_A2Up0.2369767070
GSE35957Up0.8364031496
GSE36640Down-0.9364463440
GSE54402Up0.1825032832
GSE9593Down-0.1696632186
GSE43922Down-0.0588331095
GSE24585Down-0.3397242892
GSE37065Up0.4259396310
GSE28863_A1Down-0.1764957080
GSE28863_A2Down-0.2557202834
GSE28863_A3Up0.3085485896
GSE28863_A4Down-0.4173431363
GSE48662Down-0.0088473992

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-223-3pMIMAT0000280MIRT006374Luciferase reporter assay//Western blotFunctional MTI21628394
hsa-miR-877-3pMIMAT0004950MIRT037171CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049330CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT051992CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-223-3pMIMAT00002801hsa-miR-223{Western blot}{downregulation}21628394
Entries Per Page
Displaying Page of

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.