HCSGD entry for EPB41L3
1. General information
Official gene symbol | EPB41L3 |
---|---|
Entrez ID | 23136 |
Gene full name | erythrocyte membrane protein band 4.1-like 3 |
Other gene symbols | 4.1B DAL-1 DAL1 |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network

This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0002175 | Protein localization to paranode region of axon | IEA ISS | biological_process |
GO:0003779 | Actin binding | IEA | molecular_function |
GO:0005198 | Structural molecule activity | IEA | molecular_function |
GO:0005200 | Structural constituent of cytoskeleton | TAS | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005737 | Cytoplasm | IEA | cellular_component |
GO:0005856 | Cytoskeleton | IEA | cellular_component |
GO:0005886 | Plasma membrane | NAS | cellular_component |
GO:0005911 | Cell-cell junction | IDA | cellular_component |
GO:0006915 | Apoptotic process | IEA | biological_process |
GO:0007016 | Cytoskeletal anchoring at plasma membrane | TAS | biological_process |
GO:0008150 | Biological_process | ND | biological_process |
GO:0008360 | Regulation of cell shape | IEA ISS | biological_process |
GO:0019898 | Extrinsic component of membrane | IEA | cellular_component |
GO:0030673 | Axolemma | IEA ISS | cellular_component |
GO:0030865 | Cortical cytoskeleton organization | TAS | biological_process |
GO:0030866 | Cortical actin cytoskeleton organization | IEA | biological_process |
GO:0030913 | Paranodal junction assembly | IEA ISS | biological_process |
GO:0033270 | Paranode region of axon | IEA ISS | cellular_component |
GO:0043217 | Myelin maintenance | IEA ISS | biological_process |
GO:0044224 | Juxtaparanode region of axon | IEA ISS | cellular_component |
GO:0048812 | Neuron projection morphogenesis | IEA ISS | biological_process |
GO:0071205 | Protein localization to juxtaparanode region of axon | IEA ISS | biological_process |
GO:0072659 | Protein localization to plasma membrane | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.1516759964 | 0.1097787698 | 0.7773298871 | 0.6343549945 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.1955595262 |
GSE13712_SHEAR | Up | 0.3974920660 |
GSE13712_STATIC | Up | 0.5442158842 |
GSE19018 | Down | -0.1059018676 |
GSE19899_A1 | Down | -0.2569753411 |
GSE19899_A2 | Up | 0.6162699573 |
PubMed_21979375_A1 | Up | 0.3148893442 |
PubMed_21979375_A2 | Up | 0.2369767070 |
GSE35957 | Up | 0.8364031496 |
GSE36640 | Down | -0.9364463440 |
GSE54402 | Up | 0.1825032832 |
GSE9593 | Down | -0.1696632186 |
GSE43922 | Down | -0.0588331095 |
GSE24585 | Down | -0.3397242892 |
GSE37065 | Up | 0.4259396310 |
GSE28863_A1 | Down | -0.1764957080 |
GSE28863_A2 | Down | -0.2557202834 |
GSE28863_A3 | Up | 0.3085485896 |
GSE28863_A4 | Down | -0.4173431363 |
GSE48662 | Down | -0.0088473992 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
---|---|---|---|---|---|
hsa-miR-223-3p | MIMAT0000280 | MIRT006374 | Luciferase reporter assay//Western blot | Functional MTI | 21628394 |
hsa-miR-877-3p | MIMAT0004950 | MIRT037171 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-miR-92a-3p | MIMAT0000092 | MIRT049330 | CLASH | Functional MTI (Weak) | 23622248 |
hsa-let-7b-5p | MIMAT0000063 | MIRT051992 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
---|---|---|---|---|---|---|---|
hsa-miR-223-3p | MIMAT0000280 | 1 | hsa-miR-223 | {Western blot} | {downregulation} | 21628394 |
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