HCSGD entry for EPB41L3


1. General information

Official gene symbolEPB41L3
Entrez ID23136
Gene full nameerythrocyte membrane protein band 4.1-like 3
Other gene symbols4.1B DAL-1 DAL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002175Protein localization to paranode region of axonIEA ISSbiological_process
GO:0003779Actin bindingIEAmolecular_function
GO:0005198Structural molecule activityIEAmolecular_function
GO:0005200Structural constituent of cytoskeletonTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneNAScellular_component
GO:0005911Cell-cell junctionIDAcellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0007016Cytoskeletal anchoring at plasma membraneTASbiological_process
GO:0008150Biological_processNDbiological_process
GO:0008360Regulation of cell shapeIEA ISSbiological_process
GO:0019898Extrinsic component of membraneIEAcellular_component
GO:0030673AxolemmaIEA ISScellular_component
GO:0030865Cortical cytoskeleton organizationTASbiological_process
GO:0030866Cortical actin cytoskeleton organizationIEAbiological_process
GO:0030913Paranodal junction assemblyIEA ISSbiological_process
GO:0033270Paranode region of axonIEA ISScellular_component
GO:0043217Myelin maintenanceIEA ISSbiological_process
GO:0044224Juxtaparanode region of axonIEA ISScellular_component
GO:0048812Neuron projection morphogenesisIEA ISSbiological_process
GO:0071205Protein localization to juxtaparanode region of axonIEA ISSbiological_process
GO:0072659Protein localization to plasma membraneIEA ISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15167599640.10977876980.77732988710.6343549945

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1955595262
GSE13712_SHEARUp0.3974920660
GSE13712_STATICUp0.5442158842
GSE19018Down-0.1059018676
GSE19899_A1Down-0.2569753411
GSE19899_A2Up0.6162699573
PubMed_21979375_A1Up0.3148893442
PubMed_21979375_A2Up0.2369767070
GSE35957Up0.8364031496
GSE36640Down-0.9364463440
GSE54402Up0.1825032832
GSE9593Down-0.1696632186
GSE43922Down-0.0588331095
GSE24585Down-0.3397242892
GSE37065Up0.4259396310
GSE28863_A1Down-0.1764957080
GSE28863_A2Down-0.2557202834
GSE28863_A3Up0.3085485896
GSE28863_A4Down-0.4173431363
GSE48662Down-0.0088473992

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-223-3pMIMAT0000280MIRT006374Luciferase reporter assay//Western blotFunctional MTI21628394
hsa-miR-877-3pMIMAT0004950MIRT037171CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049330CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT051992CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-223-3pMIMAT00002801hsa-miR-223{Western blot}{downregulation}21628394
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.