HCSGD entry for IQSEC2
1. General information
| Official gene symbol | IQSEC2 |
|---|---|
| Entrez ID | 23096 |
| Gene full name | IQ motif and Sec7 domain 2 |
| Other gene symbols | BRAG1 MRX1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005086 | ARF guanyl-nucleotide exchange factor activity | IBA | molecular_function |
| GO:0005634 | Nucleus | IBA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005802 | Trans-Golgi network | IBA | cellular_component |
| GO:0016192 | Vesicle-mediated transport | IBA | biological_process |
| GO:0030036 | Actin cytoskeleton organization | IBA | biological_process |
| GO:0030054 | Cell junction | IBA | cellular_component |
| GO:0032012 | Regulation of ARF protein signal transduction | IEA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2207555716 | 0.9537836556 | 0.9019175229 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0370446468 |
| GSE13712_SHEAR | Down | -0.3510669355 |
| GSE13712_STATIC | Down | -0.0669821288 |
| GSE19018 | Down | -0.0489340573 |
| GSE19899_A1 | Up | 0.0915763000 |
| GSE19899_A2 | Up | 0.1683356726 |
| PubMed_21979375_A1 | Up | 0.0915498996 |
| PubMed_21979375_A2 | Up | 0.2919309153 |
| GSE35957 | Up | 0.0081568980 |
| GSE36640 | Up | 0.4608628993 |
| GSE54402 | Down | -0.0294385515 |
| GSE9593 | Up | 0.1583431010 |
| GSE43922 | Up | 0.2145261803 |
| GSE24585 | Up | 0.2339608943 |
| GSE37065 | Up | 0.0560568351 |
| GSE28863_A1 | Up | 0.0382808023 |
| GSE28863_A2 | Down | -0.0307483440 |
| GSE28863_A3 | Up | 0.1462527271 |
| GSE28863_A4 | Up | 0.0174906254 |
| GSE48662 | Up | 0.3746377804 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
