HCSGD entry for IQSEC2


1. General information

Official gene symbolIQSEC2
Entrez ID23096
Gene full nameIQ motif and Sec7 domain 2
Other gene symbolsBRAG1 MRX1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005086ARF guanyl-nucleotide exchange factor activityIBAmolecular_function
GO:0005634NucleusIBAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005802Trans-Golgi networkIBAcellular_component
GO:0016192Vesicle-mediated transportIBAbiological_process
GO:0030036Actin cytoskeleton organizationIBAbiological_process
GO:0030054Cell junctionIBAcellular_component
GO:0032012Regulation of ARF protein signal transductionIEAbiological_process
GO:0043087Regulation of GTPase activityIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.22075557160.95378365560.90191752291.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0370446468
GSE13712_SHEARDown-0.3510669355
GSE13712_STATICDown-0.0669821288
GSE19018Down-0.0489340573
GSE19899_A1Up0.0915763000
GSE19899_A2Up0.1683356726
PubMed_21979375_A1Up0.0915498996
PubMed_21979375_A2Up0.2919309153
GSE35957Up0.0081568980
GSE36640Up0.4608628993
GSE54402Down-0.0294385515
GSE9593Up0.1583431010
GSE43922Up0.2145261803
GSE24585Up0.2339608943
GSE37065Up0.0560568351
GSE28863_A1Up0.0382808023
GSE28863_A2Down-0.0307483440
GSE28863_A3Up0.1462527271
GSE28863_A4Up0.0174906254
GSE48662Up0.3746377804

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.