HCSGD entry for KIF1B


1. General information

Official gene symbolKIF1B
Entrez ID23095
Gene full namekinesin family member 1B
Other gene symbolsCMT2 CMT2A CMT2A1 HMSNII KLP NBLST1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003777Microtubule motor activityISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionIEAcellular_component
GO:0005871Kinesin complexIEAcellular_component
GO:0005874MicrotubuleIEAcellular_component
GO:0005875Microtubule associated complexISScellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0007018Microtubule-based movementISSbiological_process
GO:0007270Neuron-neuron synaptic transmissionISSbiological_process
GO:0007274Neuromuscular synaptic transmissionISSbiological_process
GO:0008017Microtubule bindingIEAmolecular_function
GO:0008089Anterograde axon cargo transportISSbiological_process
GO:0016887ATPase activityISSmolecular_function
GO:0019894Kinesin bindingTASmolecular_function
GO:0030659Cytoplasmic vesicle membraneISScellular_component
GO:0030705Cytoskeleton-dependent intracellular transportISSbiological_process
GO:0031410Cytoplasmic vesicleISScellular_component
GO:0043005Neuron projectionISScellular_component
GO:0047497Mitochondrion transport along microtubuleIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.14169594620.78187751610.75610612201.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2089236050
GSE13712_SHEARUp0.0145340793
GSE13712_STATICUp0.0375367672
GSE19018Down-0.0657616455
GSE19899_A1Up0.0913458743
GSE19899_A2Up0.3803698196
PubMed_21979375_A1Up0.5356531100
PubMed_21979375_A2Up0.4077429462
GSE35957Up0.0826659419
GSE36640Up0.2708438983
GSE54402Up0.1925594976
GSE9593Up0.0073447413
GSE43922Up0.0589632592
GSE24585Up0.0363186302
GSE37065Down-0.0177137147
GSE28863_A1Up0.6938825363
GSE28863_A2Up0.9227423540
GSE28863_A3Down-0.4707861336
GSE28863_A4Down-0.2631724698
GSE48662Down-0.3366793432

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016600MicroarrayFunctional MTI (Weak)20304954
hsa-miR-9-5pMIMAT0000441MIRT021443MicroarrayFunctional MTI (Weak)17612493
hsa-miR-124-3pMIMAT0000422MIRT023106MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT030116MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT031988MicroarrayFunctional MTI (Weak)21199864
hsa-miR-27b-3pMIMAT0000419MIRT046178CLASHFunctional MTI (Weak)23622248
hsa-let-7c-5pMIMAT0000064MIRT051831CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.