HCSGD entry for KIF1B
1. General information
| Official gene symbol | KIF1B |
|---|---|
| Entrez ID | 23095 |
| Gene full name | kinesin family member 1B |
| Other gene symbols | CMT2 CMT2A CMT2A1 HMSNII KLP NBLST1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003777 | Microtubule motor activity | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005871 | Kinesin complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0005875 | Microtubule associated complex | ISS | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007018 | Microtubule-based movement | ISS | biological_process |
| GO:0007270 | Neuron-neuron synaptic transmission | ISS | biological_process |
| GO:0007274 | Neuromuscular synaptic transmission | ISS | biological_process |
| GO:0008017 | Microtubule binding | IEA | molecular_function |
| GO:0008089 | Anterograde axon cargo transport | ISS | biological_process |
| GO:0016887 | ATPase activity | ISS | molecular_function |
| GO:0019894 | Kinesin binding | TAS | molecular_function |
| GO:0030659 | Cytoplasmic vesicle membrane | ISS | cellular_component |
| GO:0030705 | Cytoskeleton-dependent intracellular transport | ISS | biological_process |
| GO:0031410 | Cytoplasmic vesicle | ISS | cellular_component |
| GO:0043005 | Neuron projection | ISS | cellular_component |
| GO:0047497 | Mitochondrion transport along microtubule | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1416959462 | 0.7818775161 | 0.7561061220 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2089236050 |
| GSE13712_SHEAR | Up | 0.0145340793 |
| GSE13712_STATIC | Up | 0.0375367672 |
| GSE19018 | Down | -0.0657616455 |
| GSE19899_A1 | Up | 0.0913458743 |
| GSE19899_A2 | Up | 0.3803698196 |
| PubMed_21979375_A1 | Up | 0.5356531100 |
| PubMed_21979375_A2 | Up | 0.4077429462 |
| GSE35957 | Up | 0.0826659419 |
| GSE36640 | Up | 0.2708438983 |
| GSE54402 | Up | 0.1925594976 |
| GSE9593 | Up | 0.0073447413 |
| GSE43922 | Up | 0.0589632592 |
| GSE24585 | Up | 0.0363186302 |
| GSE37065 | Down | -0.0177137147 |
| GSE28863_A1 | Up | 0.6938825363 |
| GSE28863_A2 | Up | 0.9227423540 |
| GSE28863_A3 | Down | -0.4707861336 |
| GSE28863_A4 | Down | -0.2631724698 |
| GSE48662 | Down | -0.3366793432 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016600 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-9-5p | MIMAT0000441 | MIRT021443 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT023106 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030116 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031988 | Microarray | Functional MTI (Weak) | 21199864 |
| hsa-miR-27b-3p | MIMAT0000419 | MIRT046178 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051831 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
