HCSGD entry for FOXD2

1. General information

Official gene symbolFOXD2
Entrez ID2306
Gene full nameforkhead box D2
Other gene symbolsFKHL17 FREAC-9 FREAC9
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIBAbiological_process
GO:0001658Branching involved in ureteric bud morphogenesisIBAbiological_process
GO:0001755Neural crest cell migrationIBAbiological_process
GO:0001822Kidney developmentIBAbiological_process
GO:0003690Double-stranded DNA bindingIBAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityIBAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIBAcellular_component
GO:0006366Transcription from RNA polymerase II promoterIBAbiological_process
GO:0007389Pattern specification processIBAbiological_process
GO:0007422Peripheral nervous system developmentIBAbiological_process
GO:0008134Transcription factor bindingIBAmolecular_function
GO:0008301DNA binding, bendingIBAmolecular_function
GO:0009790Embryo developmentIBAbiological_process
GO:0030318Melanocyte differentiationIBAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIBAbiological_process
GO:0048484Enteric nervous system developmentIBAbiological_process
GO:0048485Sympathetic nervous system developmentIBAbiological_process
GO:0048846Axon extension involved in axon guidanceIBAbiological_process
GO:0048937Lateral line nerve glial cell developmentIBAbiological_process
GO:0050935Iridophore differentiationIBAbiological_process
GO:0051090Regulation of sequence-specific DNA binding transcription factor activityIBAbiological_process
GO:0051216Cartilage developmentIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.16911430420.94260449450.80946673941.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0406148887
GSE13712_SHEARUp0.0391807542
GSE13712_STATICDown-0.0729209131
GSE19018Up0.1422388797
GSE19899_A1Up0.2172404465
GSE19899_A2Down-0.0168791491
PubMed_21979375_A1Up0.3004456621
PubMed_21979375_A2Up0.2782541709
GSE35957Up0.0145886839
GSE36640Down-0.1324310531
GSE54402Up0.0046551553
GSE9593Up0.0654798030
GSE43922Up0.2322828375
GSE24585Up0.1568281323
GSE37065Down-0.1174359409
GSE28863_A1Up0.0716360787
GSE28863_A2Up0.1241431245
GSE28863_A3Up0.3704791366
GSE28863_A4Up0.1422984393
GSE48662Up0.0642694335

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018455MicroarrayFunctional MTI (Weak)18185580
hsa-miR-26b-5pMIMAT0000083MIRT029980MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.