HCSGD entry for FOXD2
1. General information
| Official gene symbol | FOXD2 |
|---|---|
| Entrez ID | 2306 |
| Gene full name | forkhead box D2 |
| Other gene symbols | FKHL17 FREAC-9 FREAC9 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IBA | biological_process |
| GO:0001658 | Branching involved in ureteric bud morphogenesis | IBA | biological_process |
| GO:0001755 | Neural crest cell migration | IBA | biological_process |
| GO:0001822 | Kidney development | IBA | biological_process |
| GO:0003690 | Double-stranded DNA binding | IBA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | TAS | molecular_function |
| GO:0003705 | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity | IBA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005667 | Transcription factor complex | IBA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | IBA | biological_process |
| GO:0007389 | Pattern specification process | IBA | biological_process |
| GO:0007422 | Peripheral nervous system development | IBA | biological_process |
| GO:0008134 | Transcription factor binding | IBA | molecular_function |
| GO:0008301 | DNA binding, bending | IBA | molecular_function |
| GO:0009790 | Embryo development | IBA | biological_process |
| GO:0030318 | Melanocyte differentiation | IBA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IBA | biological_process |
| GO:0048484 | Enteric nervous system development | IBA | biological_process |
| GO:0048485 | Sympathetic nervous system development | IBA | biological_process |
| GO:0048846 | Axon extension involved in axon guidance | IBA | biological_process |
| GO:0048937 | Lateral line nerve glial cell development | IBA | biological_process |
| GO:0050935 | Iridophore differentiation | IBA | biological_process |
| GO:0051090 | Regulation of sequence-specific DNA binding transcription factor activity | IBA | biological_process |
| GO:0051216 | Cartilage development | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1691143042 | 0.9426044945 | 0.8094667394 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0406148887 |
| GSE13712_SHEAR | Up | 0.0391807542 |
| GSE13712_STATIC | Down | -0.0729209131 |
| GSE19018 | Up | 0.1422388797 |
| GSE19899_A1 | Up | 0.2172404465 |
| GSE19899_A2 | Down | -0.0168791491 |
| PubMed_21979375_A1 | Up | 0.3004456621 |
| PubMed_21979375_A2 | Up | 0.2782541709 |
| GSE35957 | Up | 0.0145886839 |
| GSE36640 | Down | -0.1324310531 |
| GSE54402 | Up | 0.0046551553 |
| GSE9593 | Up | 0.0654798030 |
| GSE43922 | Up | 0.2322828375 |
| GSE24585 | Up | 0.1568281323 |
| GSE37065 | Down | -0.1174359409 |
| GSE28863_A1 | Up | 0.0716360787 |
| GSE28863_A2 | Up | 0.1241431245 |
| GSE28863_A3 | Up | 0.3704791366 |
| GSE28863_A4 | Up | 0.1422984393 |
| GSE48662 | Up | 0.0642694335 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018455 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029980 | Microarray | Functional MTI (Weak) | 19088304 |
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