HCSGD entry for EXOSC7

1. General information

Official gene symbolEXOSC7
Entrez ID23016
Gene full nameexosome component 7
Other gene symbolsEAP1 RRP42 Rrp42p hRrp42p p8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00001753'-5'-exoribonuclease activityTASmolecular_function
GO:0000178Exosome (RNase complex)IDA TAScellular_component
GO:0000288Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decayTASbiological_process
GO:0003723RNA bindingTASmolecular_function
GO:0004532Exoribonuclease activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005730NucleolusIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006364RRNA processingTASbiological_process
GO:0006401RNA catabolic processNASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0043928Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decayTASbiological_process
GO:0090305Nucleic acid phosphodiester bond hydrolysisTASbiological_process
GO:0090501RNA phosphodiester bond hydrolysisTASbiological_process
GO:0090503RNA phosphodiester bond hydrolysis, exonucleolyticTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53126788880.69116136540.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2481352182
GSE13712_SHEARUp0.1755464533
GSE13712_STATICUp0.1520658511
GSE19018Down-0.0724031413
GSE19899_A1Up0.0167816481
GSE19899_A2Up0.4653478299
PubMed_21979375_A1Up0.0511728380
PubMed_21979375_A2Down-0.1335672447
GSE35957Up0.0326205987
GSE36640Down-0.2660665752
GSE54402Up0.0869793286
GSE9593Up0.3372464071
GSE43922Up0.1444697117
GSE24585Down-0.2017638444
GSE37065Down-0.0615755551
GSE28863_A1Up0.0106376778
GSE28863_A2Down-0.1224125419
GSE28863_A3Down-0.3220343786
GSE28863_A4Up0.0329226995
GSE48662Down-0.1888154209

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.