HCSGD entry for EXOSC7

1. General information

Official gene symbolEXOSC7
Entrez ID23016
Gene full nameexosome component 7
Other gene symbolsEAP1 RRP42 Rrp42p hRrp42p p8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00001753'-5'-exoribonuclease activityTASmolecular_function
GO:0000178Exosome (RNase complex)IDA TAScellular_component
GO:0000288Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decayTASbiological_process
GO:0003723RNA bindingTASmolecular_function
GO:0004532Exoribonuclease activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005730NucleolusIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006364RRNA processingTASbiological_process
GO:0006401RNA catabolic processNASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0043928Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decayTASbiological_process
GO:0090305Nucleic acid phosphodiester bond hydrolysisTASbiological_process
GO:0090501RNA phosphodiester bond hydrolysisTASbiological_process
GO:0090503RNA phosphodiester bond hydrolysis, exonucleolyticTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53126788880.69116136540.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2481352182
GSE13712_SHEARUp0.1755464533
GSE13712_STATICUp0.1520658511
GSE19018Down-0.0724031413
GSE19899_A1Up0.0167816481
GSE19899_A2Up0.4653478299
PubMed_21979375_A1Up0.0511728380
PubMed_21979375_A2Down-0.1335672447
GSE35957Up0.0326205987
GSE36640Down-0.2660665752
GSE54402Up0.0869793286
GSE9593Up0.3372464071
GSE43922Up0.1444697117
GSE24585Down-0.2017638444
GSE37065Down-0.0615755551
GSE28863_A1Up0.0106376778
GSE28863_A2Down-0.1224125419
GSE28863_A3Down-0.3220343786
GSE28863_A4Up0.0329226995
GSE48662Down-0.1888154209

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.