HCSGD entry for PTGR1
1. General information
| Official gene symbol | PTGR1 |
|---|---|
| Entrez ID | 22949 |
| Gene full name | prostaglandin reductase 1 |
| Other gene symbols | LTB4DH PGR1 ZADH3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006691 | Leukotriene metabolic process | NAS TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0009636 | Response to toxic substance | IEA | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0019369 | Arachidonic acid metabolic process | TAS | biological_process |
| GO:0019371 | Cyclooxygenase pathway | TAS | biological_process |
| GO:0032440 | 2-alkenal reductase [NAD(P)] activity | IEA | molecular_function |
| GO:0036132 | 13-prostaglandin reductase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0047522 | 15-oxoprostaglandin 13-oxidase activity | IEA | molecular_function |
| GO:2001300 | Lipoxin metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1041042666 | 0.2466969910 | 0.6709423115 | 0.9555830097 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.1304391544 |
| GSE13712_SHEAR | Down | -0.0639676078 |
| GSE13712_STATIC | Up | 0.0523536143 |
| GSE19018 | Up | 0.1290905967 |
| GSE19899_A1 | Up | 0.1583440165 |
| GSE19899_A2 | Down | -0.4722746399 |
| PubMed_21979375_A1 | Down | -0.1896494565 |
| PubMed_21979375_A2 | Down | -0.5743824599 |
| GSE35957 | Down | -0.7039310277 |
| GSE36640 | Up | 0.0890295250 |
| GSE54402 | Down | -0.3220929790 |
| GSE9593 | Up | 0.5280433529 |
| GSE43922 | Down | -0.0219654625 |
| GSE24585 | Up | 0.7277902277 |
| GSE37065 | Up | 0.1949790249 |
| GSE28863_A1 | Up | 0.3424837063 |
| GSE28863_A2 | Up | 0.4917835960 |
| GSE28863_A3 | Down | -0.3193930874 |
| GSE28863_A4 | Down | -0.1240692731 |
| GSE48662 | Down | -0.5485030107 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2'-Monophosphoadenosine 5'-Diphosphoribose | DB03461 | EXPT02293 |
| Para-Coumaric Acid | DB04066 | EXPT01706 |
| (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID | DB07177 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
