HCSGD entry for PTGR1

1. General information

Official gene symbolPTGR1
Entrez ID22949
Gene full nameprostaglandin reductase 1
Other gene symbolsLTB4DH PGR1 ZADH3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005737CytoplasmIEAcellular_component
GO:0006691Leukotriene metabolic processNAS TASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009636Response to toxic substanceIEAbiological_process
GO:0016491Oxidoreductase activityIEAmolecular_function
GO:0019369Arachidonic acid metabolic processTASbiological_process
GO:0019371Cyclooxygenase pathwayTASbiological_process
GO:00324402-alkenal reductase [NAD(P)] activityIEAmolecular_function
GO:003613213-prostaglandin reductase activityIEAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:004752215-oxoprostaglandin 13-oxidase activityIEAmolecular_function
GO:2001300Lipoxin metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10410426660.24669699100.67094231150.9555830097

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.1304391544
GSE13712_SHEARDown-0.0639676078
GSE13712_STATICUp0.0523536143
GSE19018Up0.1290905967
GSE19899_A1Up0.1583440165
GSE19899_A2Down-0.4722746399
PubMed_21979375_A1Down-0.1896494565
PubMed_21979375_A2Down-0.5743824599
GSE35957Down-0.7039310277
GSE36640Up0.0890295250
GSE54402Down-0.3220929790
GSE9593Up0.5280433529
GSE43922Down-0.0219654625
GSE24585Up0.7277902277
GSE37065Up0.1949790249
GSE28863_A1Up0.3424837063
GSE28863_A2Up0.4917835960
GSE28863_A3Down-0.3193930874
GSE28863_A4Down-0.1240692731
GSE48662Down-0.5485030107

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2'-Monophosphoadenosine 5'-DiphosphoriboseDB03461 EXPT02293
Para-Coumaric AcidDB04066 EXPT01706
(5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACIDDB07177 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.