HCSGD entry for EFEMP1


1. General information

Official gene symbolEFEMP1
Entrez ID2202
Gene full nameEGF containing fibulin-like extracellular matrix protein 1
Other gene symbolsDHRD DRAD FBLN3 FBNL FIBL-3 MLVT MTLV S1-5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005006Epidermal growth factor-activated receptor activityIDAmolecular_function
GO:0005154Epidermal growth factor receptor bindingIDAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedIDAbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayIDAbiological_process
GO:0007601Visual perceptionTASbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0018108Peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0031012Extracellular matrixIDAcellular_component
GO:0032331Negative regulation of chondrocyte differentiationIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04324947000.00007682080.46293993490.0148676471

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.3798783927
GSE13712_SHEARDown-0.4240475480
GSE13712_STATICDown-0.4943438338
GSE19018Down-0.1884459833
GSE19899_A1Down-3.5322544304
GSE19899_A2Down-4.2228708582
PubMed_21979375_A1Down-4.9467849017
PubMed_21979375_A2Down-5.2495623091
GSE35957Up0.7678334506
GSE36640Up0.8998599528
GSE54402Down-4.4292310684
GSE9593Up0.2147405151
GSE43922Down-3.2954476870
GSE24585Down-0.3412711315
GSE37065Down-0.0826480303
GSE28863_A1Up0.4124472480
GSE28863_A2Up2.3718871319
GSE28863_A3Up1.0877519477
GSE28863_A4Up0.4408021403
GSE48662Down-0.2156220528

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.