HCSGD entry for EFEMP1

1. General information

Official gene symbolEFEMP1
Entrez ID2202
Gene full nameEGF containing fibulin-like extracellular matrix protein 1
Other gene symbolsDHRD DRAD FBLN3 FBNL FIBL-3 MLVT MTLV S1-5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005006Epidermal growth factor-activated receptor activityIDAmolecular_function
GO:0005154Epidermal growth factor receptor bindingIDAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedIDAbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayIDAbiological_process
GO:0007601Visual perceptionTASbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0018108Peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0030198Extracellular matrix organizationTASbiological_process
GO:0031012Extracellular matrixIDAcellular_component
GO:0032331Negative regulation of chondrocyte differentiationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04324947000.00007682080.46293993490.0148676471

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.3798783927
GSE13712_SHEARDown-0.4240475480
GSE13712_STATICDown-0.4943438338
GSE19018Down-0.1884459833
GSE19899_A1Down-3.5322544304
GSE19899_A2Down-4.2228708582
PubMed_21979375_A1Down-4.9467849017
PubMed_21979375_A2Down-5.2495623091
GSE35957Up0.7678334506
GSE36640Up0.8998599528
GSE54402Down-4.4292310684
GSE9593Up0.2147405151
GSE43922Down-3.2954476870
GSE24585Down-0.3412711315
GSE37065Down-0.0826480303
GSE28863_A1Up0.4124472480
GSE28863_A2Up2.3718871319
GSE28863_A3Up1.0877519477
GSE28863_A4Up0.4408021403
GSE48662Down-0.2156220528

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.