HCSGD entry for EXT2

1. General information

Official gene symbolEXT2
Entrez ID2132
Gene full nameexostosin glycosyltransferase 2
Other gene symbolsSOTV
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0001503OssificationIMPbiological_process
GO:0001707Mesoderm formationIEAbiological_process
GO:0005783Endoplasmic reticulumIEA ISScellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005794Golgi apparatusIEA ISScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006024Glycosaminoglycan biosynthetic processIDA TASbiological_process
GO:0006486Protein glycosylationIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0008375Acetylglucosaminyltransferase activityIDA IEAmolecular_function
GO:0015012Heparan sulfate proteoglycan biosynthetic processIEA IMPbiological_process
GO:0015014Heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic processIMPbiological_process
GO:0015020Glucuronosyltransferase activityIDA IEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016757Transferase activity, transferring glycosyl groupsIDAmolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0031227Intrinsic component of endoplasmic reticulum membraneIEAcellular_component
GO:0033692Cellular polysaccharide biosynthetic processIDAbiological_process
GO:0042328Heparan sulfate N-acetylglucosaminyltransferase activityNASmolecular_function
GO:0042803Protein homodimerization activityIDA IEAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0050508Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activityIEAmolecular_function
GO:0050509N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activityNASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12634859240.32356470120.72453623091.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2130556695
GSE13712_SHEARDown-0.4103977959
GSE13712_STATICUp0.0023481197
GSE19018Up0.8205493120
GSE19899_A1Down-0.7229988530
GSE19899_A2Up0.1659537557
PubMed_21979375_A1Down-0.1637426442
PubMed_21979375_A2Up0.0786654521
GSE35957Down-0.0095810245
GSE36640Up0.6312103256
GSE54402Down-0.6165785088
GSE9593Up0.4683315090
GSE43922Up0.0508048922
GSE24585Down-0.1692890782
GSE37065Up0.0813634437
GSE28863_A1Up0.3363364836
GSE28863_A2Up0.3569952374
GSE28863_A3Down-0.5820222211
GSE28863_A4Up0.0755033133
GSE48662Up0.0848573724

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029899MicroarrayFunctional MTI (Weak)19088304
hsa-miR-34a-5pMIMAT0000255MIRT047352CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.