HCSGD entry for EXT2

1. General information

Official gene symbolEXT2
Entrez ID2132
Gene full nameexostosin glycosyltransferase 2
Other gene symbolsSOTV
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0001503OssificationIMPbiological_process
GO:0001707Mesoderm formationIEAbiological_process
GO:0005783Endoplasmic reticulumIEA ISScellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005794Golgi apparatusIEA ISScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006024Glycosaminoglycan biosynthetic processIDA TASbiological_process
GO:0006486Protein glycosylationIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0008375Acetylglucosaminyltransferase activityIDA IEAmolecular_function
GO:0015012Heparan sulfate proteoglycan biosynthetic processIEA IMPbiological_process
GO:0015014Heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic processIMPbiological_process
GO:0015020Glucuronosyltransferase activityIDA IEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0016757Transferase activity, transferring glycosyl groupsIDAmolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0030203Glycosaminoglycan metabolic processTASbiological_process
GO:0031227Intrinsic component of endoplasmic reticulum membraneIEAcellular_component
GO:0033692Cellular polysaccharide biosynthetic processIDAbiological_process
GO:0042328Heparan sulfate N-acetylglucosaminyltransferase activityNASmolecular_function
GO:0042803Protein homodimerization activityIDA IEAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0050508Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activityIEAmolecular_function
GO:0050509N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activityNASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12634859240.32356470120.72453623091.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2130556695
GSE13712_SHEARDown-0.4103977959
GSE13712_STATICUp0.0023481197
GSE19018Up0.8205493120
GSE19899_A1Down-0.7229988530
GSE19899_A2Up0.1659537557
PubMed_21979375_A1Down-0.1637426442
PubMed_21979375_A2Up0.0786654521
GSE35957Down-0.0095810245
GSE36640Up0.6312103256
GSE54402Down-0.6165785088
GSE9593Up0.4683315090
GSE43922Up0.0508048922
GSE24585Down-0.1692890782
GSE37065Up0.0813634437
GSE28863_A1Up0.3363364836
GSE28863_A2Up0.3569952374
GSE28863_A3Down-0.5820222211
GSE28863_A4Up0.0755033133
GSE48662Up0.0848573724

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029899MicroarrayFunctional MTI (Weak)19088304
hsa-miR-34a-5pMIMAT0000255MIRT047352CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.