HCSGD entry for ERG


1. General information

Official gene symbolERG
Entrez ID2078
Gene full namev-ets erythroblastosis virus E26 oncogene homolog (avian)
Other gene symbolserg-3 p55
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingTASmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0004871Signal transducer activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006468Protein phosphorylationTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0030529Ribonucleoprotein complexIDAcellular_component
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.31008432810.85690407660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1022465528
GSE13712_SHEARUp0.0671219323
GSE13712_STATICDown-0.0728138987
GSE19018Up0.0618654707
GSE19899_A1Up0.0097501768
GSE19899_A2Up0.0384405956
PubMed_21979375_A1Up0.7117685222
PubMed_21979375_A2Up0.0786767287
GSE35957Down-0.8285629094
GSE36640Down-0.0041527158
GSE54402Up0.1249916690
GSE9593Up0.1538587855
GSE43922Up0.0144796337
GSE24585Up0.1349243958
GSE37065Up0.3198673077
GSE28863_A1Down-0.1137317989
GSE28863_A2Down-0.0026345461
GSE28863_A3Up0.2643708435
GSE28863_A4Up0.0699530185
GSE48662Up0.0985061197

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT007094Luciferase reporter assayFunctional MTI23480797
hsa-miR-133bMIMAT0000770MIRT016692Reporter assayFunctional MTI17344217
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.