HCSGD entry for ERG
1. General information
| Official gene symbol | ERG |
|---|---|
| Entrez ID | 2078 |
| Gene full name | v-ets erythroblastosis virus E26 oncogene homolog (avian) |
| Other gene symbols | erg-3 p55 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | TAS | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008283 | Cell proliferation | TAS | biological_process |
| GO:0030529 | Ribonucleoprotein complex | IDA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3100843281 | 0.8569040766 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1022465528 |
| GSE13712_SHEAR | Up | 0.0671219323 |
| GSE13712_STATIC | Down | -0.0728138987 |
| GSE19018 | Up | 0.0618654707 |
| GSE19899_A1 | Up | 0.0097501768 |
| GSE19899_A2 | Up | 0.0384405956 |
| PubMed_21979375_A1 | Up | 0.7117685222 |
| PubMed_21979375_A2 | Up | 0.0786767287 |
| GSE35957 | Down | -0.8285629094 |
| GSE36640 | Down | -0.0041527158 |
| GSE54402 | Up | 0.1249916690 |
| GSE9593 | Up | 0.1538587855 |
| GSE43922 | Up | 0.0144796337 |
| GSE24585 | Up | 0.1349243958 |
| GSE37065 | Up | 0.3198673077 |
| GSE28863_A1 | Down | -0.1137317989 |
| GSE28863_A2 | Down | -0.0026345461 |
| GSE28863_A3 | Up | 0.2643708435 |
| GSE28863_A4 | Up | 0.0699530185 |
| GSE48662 | Up | 0.0985061197 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-145-5p | MIMAT0000437 | MIRT007094 | Luciferase reporter assay | Functional MTI | 23480797 |
| hsa-miR-133b | MIMAT0000770 | MIRT016692 | Reporter assay | Functional MTI | 17344217 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
