HCSGD entry for CELA1

1. General information

Official gene symbolCELA1
Entrez ID1990
Gene full namechymotrypsin-like elastase family, member 1
Other gene symbolsELA1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0004252Serine-type endopeptidase activityIEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0031017Exocrine pancreas developmentIEAbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0042127Regulation of cell proliferationIEAbiological_process
GO:0045595Regulation of cell differentiationIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0061113Pancreas morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91656791920.51206533950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0228014701
GSE13712_SHEARDown-0.2743913003
GSE13712_STATICDown-0.1974240333
GSE19018Down-0.1342472365
GSE19899_A1Up0.0072030866
GSE19899_A2Up0.0719695800
PubMed_21979375_A1Down-0.0148012104
PubMed_21979375_A2Down-0.1498160889
GSE35957Up0.0340952766
GSE36640Down-0.0722513150
GSE54402Down-0.0529603332
GSE9593Down-0.0573955332
GSE43922Up0.0260620311
GSE24585Up0.1344981857
GSE37065Up0.0574386919
GSE28863_A1Down-0.1214083746
GSE28863_A2Down-0.1071840628
GSE28863_A3Up0.2206023339
GSE28863_A4Up0.0302036802
GSE48662Up0.0108700779

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DimethylformamideDB01844 EXPT01224
Para-IsopropylanilineDB02114 EXPT01936
Mdl 101,146DB02341 EXPT02880
2-[5-Methanesulfonylamino-2-(4-Aminophenyl)-6-Oxo-1,6-Dihydro-1-Pyrimidinyl]-N-(3,3,3-Trifluoro-1-Isopropyl-2-Oxopropyl)AcetamideDB03202 EXPT03043
2-[4-[[(S)-1-[[(S)-2-[[(Rs)-3,3,3-Trifluoro-1-Isopropyl-2-Oxopropyl]Aminocarbonyl]Pyrrolidin-1-Yl-]Carbonyl]-2-Methylpropyl]Aminocarbonyl]Benzoylamino]Acetic AcidDB03702 EXPT01482
(Tert-Butyloxycarbonyl)-Alanyl-Alanyl-AmineDB03757 EXPT00619
N-[2-(1-Formyl-2-Methyl-Propyl)-1-(4-Piperidin-1-Yl-but-2-Enoyl)-Pyrrolidin-3-Yl]-MethanesulfonamideDB03890 EXPT00265
ONO-6818DB03925 EXPT00279
(3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acidDB06951 -
(TERT-BUTYLOXYCARBONYL)-ALANYL-AMINO ETHYL-FORMAMIDEDB07433 -
(2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATEDB07955 -
[1-(3-CHLORO-2-FORMYL-PHENYLCARBAMOYL)-2-METHYL-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTERDB07956 -
METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATEDB07957 -
(2R)-3-{[(BENZYLAMINO)CARBONYL]AMINO}-2-HYDROXYPROPANOIC ACIDDB08007 -
3-[[(METHYLAMINO)SULFONYL]AMINO]-2-OXO-6-PHENYL-N-[3,3,3-TRIFLUORO-1-(1-METHYLETHYL)-2-OXOPHENYL]-1(2H)-PYRIDINE ACETAMIDEDB08614 -
(2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACIDDB08640 -
(2S,3S)-3-FORMYL-2-({[(4-NITROPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACIDDB08641 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.