HCSGD entry for CELA1

1. General information

Official gene symbolCELA1
Entrez ID1990
Gene full namechymotrypsin-like elastase family, member 1
Other gene symbolsELA1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0004252Serine-type endopeptidase activityIEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0031017Exocrine pancreas developmentIEAbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0042127Regulation of cell proliferationIEAbiological_process
GO:0045595Regulation of cell differentiationIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0061113Pancreas morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91656791920.51206533950.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0228014701
GSE13712_SHEARDown-0.2743913003
GSE13712_STATICDown-0.1974240333
GSE19018Down-0.1342472365
GSE19899_A1Up0.0072030866
GSE19899_A2Up0.0719695800
PubMed_21979375_A1Down-0.0148012104
PubMed_21979375_A2Down-0.1498160889
GSE35957Up0.0340952766
GSE36640Down-0.0722513150
GSE54402Down-0.0529603332
GSE9593Down-0.0573955332
GSE43922Up0.0260620311
GSE24585Up0.1344981857
GSE37065Up0.0574386919
GSE28863_A1Down-0.1214083746
GSE28863_A2Down-0.1071840628
GSE28863_A3Up0.2206023339
GSE28863_A4Up0.0302036802
GSE48662Up0.0108700779

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DimethylformamideDB01844 EXPT01224
Para-IsopropylanilineDB02114 EXPT01936
Mdl 101,146DB02341 EXPT02880
2-[5-Methanesulfonylamino-2-(4-Aminophenyl)-6-Oxo-1,6-Dihydro-1-Pyrimidinyl]-N-(3,3,3-Trifluoro-1-Isopropyl-2-Oxopropyl)AcetamideDB03202 EXPT03043
2-[4-[[(S)-1-[[(S)-2-[[(Rs)-3,3,3-Trifluoro-1-Isopropyl-2-Oxopropyl]Aminocarbonyl]Pyrrolidin-1-Yl-]Carbonyl]-2-Methylpropyl]Aminocarbonyl]Benzoylamino]Acetic AcidDB03702 EXPT01482
(Tert-Butyloxycarbonyl)-Alanyl-Alanyl-AmineDB03757 EXPT00619
N-[2-(1-Formyl-2-Methyl-Propyl)-1-(4-Piperidin-1-Yl-but-2-Enoyl)-Pyrrolidin-3-Yl]-MethanesulfonamideDB03890 EXPT00265
ONO-6818DB03925 EXPT00279
(3R)-3-ethyl-N-[(4-methylphenyl)sulfonyl]-L-aspartic acidDB06951 -
(TERT-BUTYLOXYCARBONYL)-ALANYL-AMINO ETHYL-FORMAMIDEDB07433 -
(2-BROMOETHYL)(2-'FORMYL-4'-AMINOPHENYL) ACETATEDB07955 -
[1-(3-CHLORO-2-FORMYL-PHENYLCARBAMOYL)-2-METHYL-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTERDB07956 -
METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATEDB07957 -
(2R)-3-{[(BENZYLAMINO)CARBONYL]AMINO}-2-HYDROXYPROPANOIC ACIDDB08007 -
3-[[(METHYLAMINO)SULFONYL]AMINO]-2-OXO-6-PHENYL-N-[3,3,3-TRIFLUORO-1-(1-METHYLETHYL)-2-OXOPHENYL]-1(2H)-PYRIDINE ACETAMIDEDB08614 -
(2S,3S)-3-FORMYL-2-({[(4-METHYLPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACIDDB08640 -
(2S,3S)-3-FORMYL-2-({[(4-NITROPHENYL)SULFONYL]AMINO}METHYL)PENTANOIC ACIDDB08641 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.