HCSGD entry for DPEP1


1. General information

Official gene symbolDPEP1
Entrez ID1800
Gene full namedipeptidase 1 (renal)
Other gene symbolsMBD1 MDP RDP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceISScellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0006691Leukotriene metabolic processTASbiological_process
GO:0006749Glutathione metabolic processTASbiological_process
GO:0008235Metalloexopeptidase activityTASmolecular_function
GO:0008237Metallopeptidase activityIEAmolecular_function
GO:0008239Dipeptidyl-peptidase activityIEAmolecular_function
GO:0008270Zinc ion bindingIDAmolecular_function
GO:0016324Apical plasma membraneIEAcellular_component
GO:0016805Dipeptidase activityIEAmolecular_function
GO:0016999Antibiotic metabolic processIDAbiological_process
GO:0019369Arachidonic acid metabolic processTASbiological_process
GO:0030336Negative regulation of cell migrationIMPbiological_process
GO:0031225Anchored component of membraneIEAcellular_component
GO:0031528Microvillus membraneIEAcellular_component
GO:0034235GPI anchor bindingISSmolecular_function
GO:0035690Cellular response to drugIDAbiological_process
GO:0043027Cysteine-type endopeptidase inhibitor activity involved in apoptotic processIMPmolecular_function
GO:0043066Negative regulation of apoptotic processIMPbiological_process
GO:0043154Negative regulation of cysteine-type endopeptidase activity involved in apoptotic processIMPbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045177Apical part of cellIDAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
GO:0050667Homocysteine metabolic processIDAbiological_process
GO:0070062Extracellular vesicular exosomeIDAcellular_component
GO:0070573Metallodipeptidase activityIDAmolecular_function
GO:0071277Cellular response to calcium ionISSbiological_process
GO:0071732Cellular response to nitric oxideISSbiological_process
GO:0072340Cellular lactam catabolic processTASbiological_process
GO:0072341Modified amino acid bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41865716730.74891103680.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0100180978
GSE13712_SHEARUp0.2235406469
GSE13712_STATICDown-0.1073312365
GSE19018Down-0.0068046589
GSE19899_A1Up0.0118797698
GSE19899_A2Down-0.0258233392
PubMed_21979375_A1Down-0.0695860353
PubMed_21979375_A2Down-0.4207371914
GSE35957Up0.1183194886
GSE36640Down-0.0154818068
GSE54402Up0.0009022205
GSE9593Down-0.1150845339
GSE43922Up0.0389943773
GSE24585Up0.2955577405
GSE37065Down-0.0354166592
GSE28863_A1Down-0.1189174804
GSE28863_A2Down-0.1786510201
GSE28863_A3Up0.4947645304
GSE28863_A4Up0.2153443624
GSE48662Up0.3009201287

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.