HCSGD entry for DPEP1


1. General information

Official gene symbolDPEP1
Entrez ID1800
Gene full namedipeptidase 1 (renal)
Other gene symbolsMBD1 MDP RDP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceISScellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0006691Leukotriene metabolic processTASbiological_process
GO:0006749Glutathione metabolic processTASbiological_process
GO:0008235Metalloexopeptidase activityTASmolecular_function
GO:0008237Metallopeptidase activityIEAmolecular_function
GO:0008239Dipeptidyl-peptidase activityIEAmolecular_function
GO:0008270Zinc ion bindingIDAmolecular_function
GO:0016324Apical plasma membraneIEAcellular_component
GO:0016805Dipeptidase activityIEAmolecular_function
GO:0016999Antibiotic metabolic processIDAbiological_process
GO:0019369Arachidonic acid metabolic processTASbiological_process
GO:0030336Negative regulation of cell migrationIMPbiological_process
GO:0031225Anchored component of membraneIEAcellular_component
GO:0031528Microvillus membraneIEAcellular_component
GO:0034235GPI anchor bindingISSmolecular_function
GO:0035690Cellular response to drugIDAbiological_process
GO:0043027Cysteine-type endopeptidase inhibitor activity involved in apoptotic processIMPmolecular_function
GO:0043066Negative regulation of apoptotic processIMPbiological_process
GO:0043154Negative regulation of cysteine-type endopeptidase activity involved in apoptotic processIMPbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045177Apical part of cellIDAcellular_component
GO:0046872Metal ion bindingIEAmolecular_function
GO:0050667Homocysteine metabolic processIDAbiological_process
GO:0070062Extracellular vesicular exosomeIDAcellular_component
GO:0070573Metallodipeptidase activityIDAmolecular_function
GO:0071277Cellular response to calcium ionISSbiological_process
GO:0071732Cellular response to nitric oxideISSbiological_process
GO:0072340Cellular lactam catabolic processTASbiological_process
GO:0072341Modified amino acid bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.41865716730.74891103680.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0100180978
GSE13712_SHEARUp0.2235406469
GSE13712_STATICDown-0.1073312365
GSE19018Down-0.0068046589
GSE19899_A1Up0.0118797698
GSE19899_A2Down-0.0258233392
PubMed_21979375_A1Down-0.0695860353
PubMed_21979375_A2Down-0.4207371914
GSE35957Up0.1183194886
GSE36640Down-0.0154818068
GSE54402Up0.0009022205
GSE9593Down-0.1150845339
GSE43922Up0.0389943773
GSE24585Up0.2955577405
GSE37065Down-0.0354166592
GSE28863_A1Down-0.1189174804
GSE28863_A2Down-0.1786510201
GSE28863_A3Up0.4947645304
GSE28863_A4Up0.2153443624
GSE48662Up0.3009201287

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.