HCSGD entry for DYNC1LI2
1. General information
| Official gene symbol | DYNC1LI2 |
|---|---|
| Entrez ID | 1783 |
| Gene full name | dynein, cytoplasmic 1, light intermediate chain 2 |
| Other gene symbols | DNCLI2 LIC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000226 | Microtubule cytoskeleton organization | IEA | biological_process |
| GO:0003777 | Microtubule motor activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005868 | Cytoplasmic dynein complex | IEA | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0007018 | Microtubule-based movement | IEA | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0051642 | Centrosome localization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0679677710 | 0.9416948292 | 0.5605946445 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1139515899 |
| GSE13712_SHEAR | Up | 0.1199943671 |
| GSE13712_STATIC | Up | 0.1555119282 |
| GSE19018 | Up | 0.0665765252 |
| GSE19899_A1 | Up | 0.2940535868 |
| GSE19899_A2 | Up | 0.1265169263 |
| PubMed_21979375_A1 | Down | -0.3392691730 |
| PubMed_21979375_A2 | Down | -0.3561528933 |
| GSE35957 | Up | 0.2734222378 |
| GSE36640 | Up | 1.1290088533 |
| GSE54402 | Up | 0.3674505628 |
| GSE9593 | Up | 0.3887268941 |
| GSE43922 | Down | -0.0640857892 |
| GSE24585 | Up | 0.1027873308 |
| GSE37065 | Down | -0.0851700074 |
| GSE28863_A1 | Up | 0.0863294121 |
| GSE28863_A2 | Up | 0.4255871944 |
| GSE28863_A3 | Down | -0.0852835115 |
| GSE28863_A4 | Up | 0.0831717885 |
| GSE48662 | Up | 0.4333795076 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT030895 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-let-7f-5p | MIMAT0000067 | MIRT051385 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
