HCSGD entry for DYNC1LI2


1. General information

Official gene symbolDYNC1LI2
Entrez ID1783
Gene full namedynein, cytoplasmic 1, light intermediate chain 2
Other gene symbolsDNCLI2 LIC2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000226Microtubule cytoskeleton organizationIEAbiological_process
GO:0003777Microtubule motor activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005813CentrosomeIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005868Cytoplasmic dynein complexIEAcellular_component
GO:0005874MicrotubuleIEAcellular_component
GO:0006810TransportIEAbiological_process
GO:0007018Microtubule-based movementIEAbiological_process
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0051642Centrosome localizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06796777100.94169482920.56059464451.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1139515899
GSE13712_SHEARUp0.1199943671
GSE13712_STATICUp0.1555119282
GSE19018Up0.0665765252
GSE19899_A1Up0.2940535868
GSE19899_A2Up0.1265169263
PubMed_21979375_A1Down-0.3392691730
PubMed_21979375_A2Down-0.3561528933
GSE35957Up0.2734222378
GSE36640Up1.1290088533
GSE54402Up0.3674505628
GSE9593Up0.3887268941
GSE43922Down-0.0640857892
GSE24585Up0.1027873308
GSE37065Down-0.0851700074
GSE28863_A1Up0.0863294121
GSE28863_A2Up0.4255871944
GSE28863_A3Down-0.0852835115
GSE28863_A4Up0.0831717885
GSE48662Up0.4333795076

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-21-5pMIMAT0000076MIRT030895MicroarrayFunctional MTI (Weak)18591254
hsa-let-7f-5pMIMAT0000067MIRT051385CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.