HCSGD entry for DNASE1L2


1. General information

Official gene symbolDNASE1L2
Entrez ID1775
Gene full namedeoxyribonuclease I-like 2
Other gene symbolsDNAS1L2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingTASmolecular_function
GO:0004536Deoxyribonuclease activityTASmolecular_function
GO:0005509Calcium ion bindingTASmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0006259DNA metabolic processTASbiological_process
GO:0016888Endodeoxyribonuclease activity, producing 5'-phosphomonoestersIEAmolecular_function
GO:0090305Nucleic acid phosphodiester bond hydrolysisTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.30009606400.86592070210.99882756311.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0070774782
GSE13712_SHEARDown-0.0915927197
GSE13712_STATICDown-0.0667487316
GSE19018Down-0.0473153880
GSE19899_A1Down-0.0094866406
GSE19899_A2Up0.1940611859
PubMed_21979375_A1Down-0.2347610467
PubMed_21979375_A2Down-0.1022515371
GSE35957Down-0.0261012829
GSE36640Up0.0297052930
GSE54402Down-0.1626525473
GSE9593Up0.1663649963
GSE43922Up0.1338699281
GSE24585Up1.0027303223
GSE37065Down-0.0168815361
GSE28863_A1Up0.0099658749
GSE28863_A2Up0.1373515437
GSE28863_A3Up0.3353223616
GSE28863_A4Up0.0930390258
GSE48662Up0.1062772656

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.