HCSGD entry for DNASE1L2


1. General information

Official gene symbolDNASE1L2
Entrez ID1775
Gene full namedeoxyribonuclease I-like 2
Other gene symbolsDNAS1L2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingTASmolecular_function
GO:0004536Deoxyribonuclease activityTASmolecular_function
GO:0005509Calcium ion bindingTASmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0006259DNA metabolic processTASbiological_process
GO:0016888Endodeoxyribonuclease activity, producing 5'-phosphomonoestersIEAmolecular_function
GO:0090305Nucleic acid phosphodiester bond hydrolysisTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.30009606400.86592070210.99882756311.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0070774782
GSE13712_SHEARDown-0.0915927197
GSE13712_STATICDown-0.0667487316
GSE19018Down-0.0473153880
GSE19899_A1Down-0.0094866406
GSE19899_A2Up0.1940611859
PubMed_21979375_A1Down-0.2347610467
PubMed_21979375_A2Down-0.1022515371
GSE35957Down-0.0261012829
GSE36640Up0.0297052930
GSE54402Down-0.1626525473
GSE9593Up0.1663649963
GSE43922Up0.1338699281
GSE24585Up1.0027303223
GSE37065Down-0.0168815361
GSE28863_A1Up0.0099658749
GSE28863_A2Up0.1373515437
GSE28863_A3Up0.3353223616
GSE28863_A4Up0.0930390258
GSE48662Up0.1062772656

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.