HCSGD entry for DEFA4
1. General information
| Official gene symbol | DEFA4 |
|---|---|
| Entrez ID | 1669 |
| Gene full name | defensin, alpha 4, corticostatin |
| Other gene symbols | DEF4 HNP-4 HP-4 HP4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0031640 | Killing of cells of other organism | IEA | biological_process |
| GO:0042742 | Defense response to bacterium | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0050832 | Defense response to fungus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7409555032 | 0.7659865317 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1130151371 |
| GSE13712_SHEAR | Down | -0.0345343984 |
| GSE13712_STATIC | Up | 0.1522098658 |
| GSE19018 | Up | 0.1789810507 |
| GSE19899_A1 | Up | 0.1297101645 |
| GSE19899_A2 | Down | -0.0076089454 |
| PubMed_21979375_A1 | Up | 0.2651553018 |
| PubMed_21979375_A2 | Down | -0.2543786980 |
| GSE35957 | Up | 0.0480595506 |
| GSE36640 | Up | 0.0978542401 |
| GSE54402 | Down | -0.0760848233 |
| GSE9593 | Down | -0.1330075401 |
| GSE43922 | Up | 0.0155065229 |
| GSE24585 | Up | 0.1537319191 |
| GSE37065 | Down | -0.0845704990 |
| GSE28863_A1 | Down | -0.0590305439 |
| GSE28863_A2 | Down | -0.0386438223 |
| GSE28863_A3 | Up | 0.3548938876 |
| GSE28863_A4 | Up | 0.0149682948 |
| GSE48662 | Down | -0.0525347031 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017503 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
