HCSGD entry for DEFA4


1. General information

Official gene symbolDEFA4
Entrez ID1669
Gene full namedefensin, alpha 4, corticostatin
Other gene symbolsDEF4 HNP-4 HP-4 HP4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0005796Golgi lumenTAScellular_component
GO:0031640Killing of cells of other organismIEAbiological_process
GO:0042742Defense response to bacteriumIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0050832Defense response to fungusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74095550320.76598653170.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1130151371
GSE13712_SHEARDown-0.0345343984
GSE13712_STATICUp0.1522098658
GSE19018Up0.1789810507
GSE19899_A1Up0.1297101645
GSE19899_A2Down-0.0076089454
PubMed_21979375_A1Up0.2651553018
PubMed_21979375_A2Down-0.2543786980
GSE35957Up0.0480595506
GSE36640Up0.0978542401
GSE54402Down-0.0760848233
GSE9593Down-0.1330075401
GSE43922Up0.0155065229
GSE24585Up0.1537319191
GSE37065Down-0.0845704990
GSE28863_A1Down-0.0590305439
GSE28863_A2Down-0.0386438223
GSE28863_A3Up0.3548938876
GSE28863_A4Up0.0149682948
GSE48662Down-0.0525347031

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017503MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.