HCSGD entry for DARS
1. General information
| Official gene symbol | DARS |
|---|---|
| Entrez ID | 1615 |
| Gene full name | aspartyl-tRNA synthetase |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004046 | Aminoacylase activity | TAS | molecular_function |
| GO:0004815 | Aspartate-tRNA ligase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006422 | Aspartyl-tRNA aminoacylation | IEA | biological_process |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
Entries Per Page
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8069406026 | 0.0779386383 | 0.9999902473 | 0.5285810100 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3411456878 |
| GSE13712_SHEAR | Up | 0.2972827519 |
| GSE13712_STATIC | Up | 0.2390136246 |
| GSE19018 | Up | 0.3524978705 |
| GSE19899_A1 | Down | -0.3802338793 |
| GSE19899_A2 | Down | -0.1187298388 |
| PubMed_21979375_A1 | Down | -0.1869316926 |
| PubMed_21979375_A2 | Down | -0.0761007830 |
| GSE35957 | Down | -0.7834905228 |
| GSE36640 | Down | -1.2919075712 |
| GSE54402 | Down | -0.1036747971 |
| GSE9593 | Down | -0.1786452043 |
| GSE43922 | Down | -0.0914840024 |
| GSE24585 | Down | -0.1158985266 |
| GSE37065 | Up | 0.1209164559 |
| GSE28863_A1 | Up | 0.2690426820 |
| GSE28863_A2 | Up | 0.4675615254 |
| GSE28863_A3 | Down | -0.3468873052 |
| GSE28863_A4 | Down | -0.0305400047 |
| GSE48662 | Down | -0.2243037579 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Aspartic Acid | DB00128 | NUTR00016 | EXPT01823 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
