HCSGD entry for DARS


1. General information

Official gene symbolDARS
Entrez ID1615
Gene full nameaspartyl-tRNA synthetase
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0004046Aminoacylase activityTASmolecular_function
GO:0004815Aspartate-tRNA ligase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006412TranslationTASbiological_process
GO:0006418TRNA aminoacylation for protein translationTASbiological_process
GO:0006422Aspartyl-tRNA aminoacylationIEAbiological_process
GO:0006461Protein complex assemblyTASbiological_process
GO:0010467Gene expressionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80694060260.07793863830.99999024730.5285810100

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3411456878
GSE13712_SHEARUp0.2972827519
GSE13712_STATICUp0.2390136246
GSE19018Up0.3524978705
GSE19899_A1Down-0.3802338793
GSE19899_A2Down-0.1187298388
PubMed_21979375_A1Down-0.1869316926
PubMed_21979375_A2Down-0.0761007830
GSE35957Down-0.7834905228
GSE36640Down-1.2919075712
GSE54402Down-0.1036747971
GSE9593Down-0.1786452043
GSE43922Down-0.0914840024
GSE24585Down-0.1158985266
GSE37065Up0.1209164559
GSE28863_A1Up0.2690426820
GSE28863_A2Up0.4675615254
GSE28863_A3Down-0.3468873052
GSE28863_A4Down-0.0305400047
GSE48662Down-0.2243037579

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Aspartic AcidDB00128 NUTR00016 | EXPT01823

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.