HCSGD entry for CYP24A1
1. General information
| Official gene symbol | CYP24A1 |
|---|---|
| Entrez ID | 1591 |
| Gene full name | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| Other gene symbols | CP24 CYP24 HCAI P450-CC24 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001649 | Osteoblast differentiation | IEP | biological_process |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005743 | Mitochondrial inner membrane | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0008202 | Steroid metabolic process | TAS | biological_process |
| GO:0008403 | 25-hydroxycholecalciferol-24-hydroxylase activity | IEA | molecular_function |
| GO:0016491 | Oxidoreductase activity | NAS | molecular_function |
| GO:0020037 | Heme binding | TAS | molecular_function |
| GO:0030342 | 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity | IDA | molecular_function |
| GO:0033280 | Response to vitamin D | IDA | biological_process |
| GO:0042359 | Vitamin D metabolic process | TAS | biological_process |
| GO:0042369 | Vitamin D catabolic process | NAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
| GO:0070561 | Vitamin D receptor signaling pathway | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0914724251 | 0.9365570267 | 0.6364381972 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0200315635 |
| GSE13712_SHEAR | Down | -0.0119995294 |
| GSE13712_STATIC | Down | -0.0683307322 |
| GSE19018 | Up | 0.1899225389 |
| GSE19899_A1 | Up | 0.1550957638 |
| GSE19899_A2 | Up | 0.2801453511 |
| PubMed_21979375_A1 | Up | 0.3549491786 |
| PubMed_21979375_A2 | Up | 0.1270985860 |
| GSE35957 | Up | 0.0688164237 |
| GSE36640 | Up | 0.1218027609 |
| GSE54402 | Up | 0.1818012372 |
| GSE9593 | Down | -0.1831824924 |
| GSE43922 | Up | 0.0171295148 |
| GSE24585 | Down | -0.0480632013 |
| GSE37065 | Up | 1.7243172498 |
| GSE28863_A1 | Up | 0.4169328625 |
| GSE28863_A2 | Up | 0.5826955020 |
| GSE28863_A3 | Up | 0.0871909685 |
| GSE28863_A4 | Down | -0.1141283098 |
| GSE48662 | Down | -0.0502309832 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| CTA018 | DB05024 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125b-5p | MIMAT0000423 | MIRT004408 | qRT-PCR//Luciferase reporter assay//Western blot//Northern blot//Reporter assay | Functional MTI | 19570947 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024646 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026473 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029534 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
