HCSGD entry for CYP3A5

1. General information

Official gene symbolCYP3A5
Entrez ID1577
Gene full namecytochrome P450, family 3, subfamily A, polypeptide 5
Other gene symbolsCP35 CYPIIIA5 P450PCN3 PCN3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004497Monooxygenase activityISSmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0008202Steroid metabolic processTASbiological_process
GO:0009822Alkaloid catabolic processIDAbiological_process
GO:0016491Oxidoreductase activityIDAmolecular_function
GO:0016712Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygenIEAmolecular_function
GO:0019825Oxygen bindingTASmolecular_function
GO:0020037Heme bindingIEAmolecular_function
GO:0042737Drug catabolic processIDAbiological_process
GO:0043231Intracellular membrane-bounded organelleTAScellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0070330Aromatase activityIEAmolecular_function
GO:0070989Oxidative demethylationIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07721952050.98639333610.58674797921.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1164897397
GSE13712_SHEARUp0.0325513125
GSE13712_STATICDown-0.0751879232
GSE19018Up0.1028027531
GSE19899_A1Up0.2139058311
GSE19899_A2Up0.4065918362
PubMed_21979375_A1Up0.3855106776
PubMed_21979375_A2Up0.1075033046
GSE35957Up0.2080087878
GSE36640Up0.1118835079
GSE54402Up0.6262514827
GSE9593Up0.0890802519
GSE43922Up0.8241947283
GSE24585Up0.0633452890
GSE37065Up0.1248914754
GSE28863_A1Down-0.0146594984
GSE28863_A2Down-0.0804866663
GSE28863_A3Up0.1334466964
GSE28863_A4Up0.0387710039
GSE48662Up0.0413844510

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PaliperidoneDB01267 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017425MicroarrayFunctional MTI (Weak)18185580
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.