HCSGD entry for AMOT

1. General information

Official gene symbolAMOT
Entrez ID154796
Gene full nameangiomotin
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001570VasculogenesisIEAbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0001702Gastrulation with mouth forming secondIEAbiological_process
GO:0001725Stress fiberIDAcellular_component
GO:0001726RuffleIDAcellular_component
GO:0003365Establishment of cell polarity involved in ameboidal cell migrationIEAbiological_process
GO:0004872Receptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005884Actin filamentIDAcellular_component
GO:0005923Tight junctionIDA IEAcellular_component
GO:0006935ChemotaxisIEAbiological_process
GO:0007043Cell-cell junction assemblyTASbiological_process
GO:0008180COP9 signalosomeIDAcellular_component
GO:0009897External side of plasma membraneIDAcellular_component
GO:0009986Cell surfaceIDAcellular_component
GO:0016021Integral component of membraneIDAcellular_component
GO:0016525Negative regulation of angiogenesisIDAbiological_process
GO:0030027LamellipodiumIDA IEAcellular_component
GO:0030036Actin cytoskeleton organizationIEA TASbiological_process
GO:0030139Endocytic vesicleIDAcellular_component
GO:0030334Regulation of cell migrationIDAbiological_process
GO:0031410Cytoplasmic vesicleIEAcellular_component
GO:0034260Negative regulation of GTPase activityIEAbiological_process
GO:0034613Cellular protein localizationIDA IEAbiological_process
GO:0035329Hippo signalingIGI TASbiological_process
GO:0040019Positive regulation of embryonic developmentIEAbiological_process
GO:0042074Cell migration involved in gastrulationIEAbiological_process
GO:0043116Negative regulation of vascular permeabilityIDAbiological_process
GO:0043532Angiostatin bindingIDAmolecular_function
GO:0043534Blood vessel endothelial cell migrationIEAbiological_process
GO:0043536Positive regulation of blood vessel endothelial cell migrationIDAbiological_process
GO:0045793Positive regulation of cell sizeTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionIEAbiological_process
GO:0051496Positive regulation of stress fiber assemblyTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97777441590.01144349760.99999024730.2121157042

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0538185236
GSE13712_SHEARDown-0.1436838469
GSE13712_STATICDown-0.0573314670
GSE19018Up0.1830322763
GSE19899_A1Up0.0065879127
GSE19899_A2Down-0.4061798649
PubMed_21979375_A1Up0.0920022405
PubMed_21979375_A2Down-0.1510226497
GSE35957Up0.0426082375
GSE36640Down-0.4542621525
GSE54402Down-0.3070335821
GSE9593Down-0.0792711695
GSE43922Down-0.6687436035
GSE24585Down-3.3609160531
GSE37065Up0.0247263303
GSE28863_A1Up0.0625269134
GSE28863_A2Down-0.2306218752
GSE28863_A3Down-0.0461528736
GSE28863_A4Down-0.1461973270
GSE48662Down-0.2441883851

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-340-5pMIMAT0004692MIRT019601SequencingFunctional MTI (Weak)20371350
hsa-miR-221-3pMIMAT0000278MIRT046949CLASHFunctional MTI (Weak)23622248
hsa-miR-16-5pMIMAT0000069MIRT051168CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.