HCSGD entry for AMOT

1. General information

Official gene symbolAMOT
Entrez ID154796
Gene full nameangiomotin
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001570VasculogenesisIEAbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0001702Gastrulation with mouth forming secondIEAbiological_process
GO:0001725Stress fiberIDAcellular_component
GO:0001726RuffleIDAcellular_component
GO:0003365Establishment of cell polarity involved in ameboidal cell migrationIEAbiological_process
GO:0004872Receptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005884Actin filamentIDAcellular_component
GO:0005923Tight junctionIDA IEAcellular_component
GO:0006935ChemotaxisIEAbiological_process
GO:0007043Cell-cell junction assemblyTASbiological_process
GO:0008180COP9 signalosomeIDAcellular_component
GO:0009897External side of plasma membraneIDAcellular_component
GO:0009986Cell surfaceIDAcellular_component
GO:0016021Integral component of membraneIDAcellular_component
GO:0016525Negative regulation of angiogenesisIDAbiological_process
GO:0030027LamellipodiumIDA IEAcellular_component
GO:0030036Actin cytoskeleton organizationIEA TASbiological_process
GO:0030139Endocytic vesicleIDAcellular_component
GO:0030334Regulation of cell migrationIDAbiological_process
GO:0031410Cytoplasmic vesicleIEAcellular_component
GO:0034260Negative regulation of GTPase activityIEAbiological_process
GO:0034613Cellular protein localizationIDA IEAbiological_process
GO:0035329Hippo signalingIGI TASbiological_process
GO:0040019Positive regulation of embryonic developmentIEAbiological_process
GO:0042074Cell migration involved in gastrulationIEAbiological_process
GO:0043116Negative regulation of vascular permeabilityIDAbiological_process
GO:0043532Angiostatin bindingIDAmolecular_function
GO:0043534Blood vessel endothelial cell migrationIEAbiological_process
GO:0043536Positive regulation of blood vessel endothelial cell migrationIDAbiological_process
GO:0045793Positive regulation of cell sizeTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionIEAbiological_process
GO:0051496Positive regulation of stress fiber assemblyTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97777441590.01144349760.99999024730.2121157042

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0538185236
GSE13712_SHEARDown-0.1436838469
GSE13712_STATICDown-0.0573314670
GSE19018Up0.1830322763
GSE19899_A1Up0.0065879127
GSE19899_A2Down-0.4061798649
PubMed_21979375_A1Up0.0920022405
PubMed_21979375_A2Down-0.1510226497
GSE35957Up0.0426082375
GSE36640Down-0.4542621525
GSE54402Down-0.3070335821
GSE9593Down-0.0792711695
GSE43922Down-0.6687436035
GSE24585Down-3.3609160531
GSE37065Up0.0247263303
GSE28863_A1Up0.0625269134
GSE28863_A2Down-0.2306218752
GSE28863_A3Down-0.0461528736
GSE28863_A4Down-0.1461973270
GSE48662Down-0.2441883851

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-340-5pMIMAT0004692MIRT019601SequencingFunctional MTI (Weak)20371350
hsa-miR-221-3pMIMAT0000278MIRT046949CLASHFunctional MTI (Weak)23622248
hsa-miR-16-5pMIMAT0000069MIRT051168CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.